Overview

  • Product name

  • Description

    Rabbit polyclonal to CYP2D6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat, Monkey
  • Immunogen

    Synthetic peptide corresponding to Human CYP2D6 (internal sequence) conjugated to keyhole limpet haemocyanin.
    Database link: P10635

  • Positive control

    • WB: MCF7, NIH/3T3 and H9c2 whole cell lysates. IHC-P: Human liver tissue.
  • General notes

     This product was previously labelled as Cytochrome P450 2D6

     

Properties

Applications

Our Abpromise guarantee covers the use of ab230690 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 56 kDa.
IHC-P 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.
  • Sequence similarities

    Belongs to the cytochrome P450 family.
  • Cellular localization

    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cholesterol 25-hydroxylase antibody
    • CP2D6_HUMAN antibody
    • CPD6 antibody
    • CYP2D antibody
    • CYP2D6 antibody
    • CYP2D7AP antibody
    • CYP2D7BP antibody
    • CYP2D7P2 antibody
    • CYP2D8P2 antibody
    • CYP2DL1 antibody
    • CYPIID6 antibody
    • Cytochrome P450 2D6 antibody
    • Cytochrome P450 DB1 antibody
    • Cytochrome P450 family 2 subfamily D member 6 antibody
    • Cytochrome P450 family 2 subfamily D polypeptide 6 antibody
    • Cytochrome P450-DB1 antibody
    • Debrisoquine 4 hydroxylase antibody
    • Debrisoquine 4-hydroxylase antibody
    • Flavoprotein linked monooxygenase antibody
    • Microsomal monooxygenase antibody
    • P450 DB1 antibody
    • P450C2D antibody
    • P450DB1 antibody
    • Xenobiotic monooxygenase antibody
    see all

Images

  • All lanes : Anti-CYP2D6 antibody (ab230690) at 1/500 dilution

    Lane 1 : MCF7 (human breast adenocarcinoma cell line) whole cell lysate
    Lane 2 : NIH/3T3 (mouse embryo fibroblast cell line) whole cell lysate
    Lane 3 : H9c2 (rat heart myoblast cell line) whole cell lysate

    Developed using the ECL technique.

    Predicted band size: 56 kDa

  • Formalin-fixed, paraffin-embedded human liver tissue stained for CYP2D6 with ab230690 at 1/100 dilution in immunohistochemical analysis.

References

ab230690 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab230690.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up