Anti-CYP2D6 antibody (ab4238)
Key features and details
- Rabbit polyclonal to CYP2D6
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-CYP2D6 antibody
See all CYP2D6 primary antibodies -
Description
Rabbit polyclonal to CYP2D6 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein corresponding to Human CYP2D6.
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Positive control
- WB: Recombinant human CYP2D6.
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General notes
This product was previously labelled as Cytochrome P450 2D6
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 8.00
Constituent: 0.0536% PBS -
Concentration information loading... -
Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab4238 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/1000. Predicted molecular weight: 60 kDa. |
Target
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Function
Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants. -
Sequence similarities
Belongs to the cytochrome P450 family. -
Cellular localization
Endoplasmic reticulum membrane. Microsome membrane. - Information by UniProt
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Database links
- Entrez Gene: 1565 Human
- Omim: 124030 Human
- SwissProt: P10635 Human
- Unigene: 648256 Human
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Alternative names
- Cholesterol 25-hydroxylase antibody
- CP2D6_HUMAN antibody
- CPD6 antibody
see all
Datasheets and documents
References
ab4238 has been referenced in 2 publications.
- Ocadiz-Ruiz R et al. ZBP-89 function in colonic stem cells and during butyrate-induced senescence. Oncotarget 8:94330-94344 (2017). PubMed: 29212231
- DiMaio Knych HK & Stanley SD Complementary DNA cloning, functional expression and characterization of a novel cytochrome P450, CYP2D50, from equine liver. Biochem Pharmacol 76:904-11 (2008). PubMed: 18692486
