Anti-CYP2D6 antibody (ab4238)

Submit a review Q&A (2)References (2)

Overview

  • Product name
    Anti-CYP2D6 antibody
    See all CYP2D6 primary antibodies
  • Description
    Rabbit polyclonal to CYP2D6
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human CYP2D6.

  • Positive control
    • WB: Recombinant human CYP2D6.
  • General notes

     This product was previously labelled as Cytochrome P450 2D6

     

Properties

Applications

Our Abpromise guarantee covers the use of ab4238 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 60 kDa.

Target

  • Function
    Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.
  • Sequence similarities
    Belongs to the cytochrome P450 family.
  • Cellular localization
    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links
    • Alternative names
      • Cholesterol 25-hydroxylase antibody
      • CP2D6_HUMAN antibody
      • CPD6 antibody
      • CYP2D antibody
      • CYP2D6 antibody
      • CYP2D7AP antibody
      • CYP2D7BP antibody
      • CYP2D7P2 antibody
      • CYP2D8P2 antibody
      • CYP2DL1 antibody
      • CYPIID6 antibody
      • Cytochrome P450 2D6 antibody
      • Cytochrome P450 DB1 antibody
      • Cytochrome P450 family 2 subfamily D member 6 antibody
      • Cytochrome P450 family 2 subfamily D polypeptide 6 antibody
      • Cytochrome P450-DB1 antibody
      • Debrisoquine 4 hydroxylase antibody
      • Debrisoquine 4-hydroxylase antibody
      • Flavoprotein linked monooxygenase antibody
      • Microsomal monooxygenase antibody
      • P450 DB1 antibody
      • P450C2D antibody
      • P450DB1 antibody
      • Xenobiotic monooxygenase antibody
      see all

    References

    This product has been referenced in:
    • Ocadiz-Ruiz R  et al. ZBP-89 function in colonic stem cells and during butyrate-induced senescence. Oncotarget 8:94330-94344 (2017). Read more (PubMed: 29212231) »
    • DiMaio Knych HK & Stanley SD Complementary DNA cloning, functional expression and characterization of a novel cytochrome P450, CYP2D50, from equine liver. Biochem Pharmacol 76:904-11 (2008). Read more (PubMed: 18692486) »
    See all 2 Publications for this product

    Publishing research using ab4238? Please let us know so that we can cite the reference in this datasheet.

    Customer reviews and Q&As

    Show All Reviews Q&A
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    1-2 of 2 Abreviews or Q&A

    Question

    Product code: 4238
    Inquiry: Good evening, I looking for an antibody against cytochrome P450 2D6. I already used your antibody (ab4238). Can I ask you about your distributor in Italy? It could be a problem for me to order directly to you. Thanks in advanced Best Regards

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    Answer

    Thank you for contacting us.

    You can buy the antibody directly from us. however if it is a problem then please buy it from our distributor; http://www.ricerca.it/

    I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

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    Question

    Customer is still not seeing a signal with this antibody in WB. Tried the exp. again using a 1:500 dilution. Will send a replacement. Order# 101515.

    Read More
    Answer

    Thank you for your enquiry and I'm sorry to hear that you are still experiencing difficulty with ab4238. The free of charge replacement vial is being sent to your attention on order reference # 110441 and you should receive this Tuesday. Please let me know how the replacement works out for you and if you have any additional questions.

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