Overview

  • Product name

    Anti-CYP2D6 antibody - C-terminal
    See all CYP2D6 primary antibodies
  • Description

    Goat polyclonal to CYP2D6 - C-terminal
  • Host species

    Goat
  • Specificity

    ab223490 is expected to recognize both reported isoforms (NP_000097.3; NP_001020332.2).
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Chimpanzee, Cynomolgus monkey
  • Immunogen

    Synthetic peptide corresponding to Human CYP2D6 aa 469-478 (C terminal) (Cysteine residue). (NP_000097.3).
    Sequence:

    C-PTGQPRPSHH


    Database link: P10635

  • Positive control

    • WB: Human liver lysate.
  • General notes

     This product was previously labelled as Cytochrome P450 2D6

     

Properties

Applications

Our Abpromise guarantee covers the use of ab223490 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 56 kDa).

Target

  • Function

    Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.
  • Sequence similarities

    Belongs to the cytochrome P450 family.
  • Cellular localization

    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cholesterol 25-hydroxylase antibody
    • CP2D6_HUMAN antibody
    • CPD6 antibody
    • CYP2D antibody
    • CYP2D6 antibody
    • CYP2D7AP antibody
    • CYP2D7BP antibody
    • CYP2D7P2 antibody
    • CYP2D8P2 antibody
    • CYP2DL1 antibody
    • CYPIID6 antibody
    • Cytochrome P450 2D6 antibody
    • Cytochrome P450 DB1 antibody
    • Cytochrome P450 family 2 subfamily D member 6 antibody
    • Cytochrome P450 family 2 subfamily D polypeptide 6 antibody
    • Cytochrome P450-DB1 antibody
    • Debrisoquine 4 hydroxylase antibody
    • Debrisoquine 4-hydroxylase antibody
    • Flavoprotein linked monooxygenase antibody
    • Microsomal monooxygenase antibody
    • P450 DB1 antibody
    • P450C2D antibody
    • P450DB1 antibody
    • Xenobiotic monooxygenase antibody
    see all

Images

  • Anti-CYP2D6 antibody - C-terminal (ab223490) at 2 µg/ml + Human liver lysate (in RIPA buffer) at 35 µg

    Developed using the ECL technique.

    Predicted band size: 56 kDa
    Observed band size: 55 kDa
    why is the actual band size different from the predicted?



    Primary incubation was 1 hour.

References

ab223490 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab223490.
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