Overview

  • Product name

    Anti-CYP2D6 antibody - C-terminal
    See all CYP2D6 primary antibodies
  • Description

    Rabbit polyclonal to CYP2D6 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat, Monkey
  • Immunogen

    Synthetic peptide within Human CYP2D6 (C terminal) conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: P10635

  • Positive control

    • IHC-P: Human liver tissue. WB: MCF7, NIH/3T3 and H9C2 whole cell lysates.
  • General notes

     This product was previously labelled as Cytochrome P450 2D6

     

Properties

Applications

Our Abpromise guarantee covers the use of ab230472 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100.
WB 1/500 - 1/1000. Predicted molecular weight: 56 kDa.

Target

  • Function

    Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.
  • Sequence similarities

    Belongs to the cytochrome P450 family.
  • Cellular localization

    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Cholesterol 25-hydroxylase antibody
    • CP2D6_HUMAN antibody
    • CPD6 antibody
    • CYP2D antibody
    • CYP2D6 antibody
    • CYP2D7AP antibody
    • CYP2D7BP antibody
    • CYP2D7P2 antibody
    • CYP2D8P2 antibody
    • CYP2DL1 antibody
    • CYPIID6 antibody
    • Cytochrome P450 2D6 antibody
    • Cytochrome P450 DB1 antibody
    • Cytochrome P450 family 2 subfamily D member 6 antibody
    • Cytochrome P450 family 2 subfamily D polypeptide 6 antibody
    • Cytochrome P450-DB1 antibody
    • Debrisoquine 4 hydroxylase antibody
    • Debrisoquine 4-hydroxylase antibody
    • Flavoprotein linked monooxygenase antibody
    • Microsomal monooxygenase antibody
    • P450 DB1 antibody
    • P450C2D antibody
    • P450DB1 antibody
    • Xenobiotic monooxygenase antibody
    see all

Images

  • All lanes : Anti-CYP2D6 antibody - C-terminal (ab230472) at 1/500 dilution

    Lane 1 : MCF7 (human breast adenocarcinoma cell line) whole cell lysate
    Lane 2 : NIH/3T3 (mouse embryo fibroblast cell line) whole cell lysate
    Lane 3 : H9C2 whole cell lysate

    Predicted band size: 56 kDa

  • Formalin-fixed, parrafin-embedded human liver tissue stained for CYP2D6 antibody - C-terminal using ab230472 at 1/100 dilution in immunohistochemical analysis.

References

ab230472 has not yet been referenced specifically in any publications.

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