Overview

  • Product name

  • Description

    Rabbit polyclonal to CYP46A1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Rat, Human
  • Immunogen

    Recombinant fragment within Human CYP46A1 (internal sequence). The exact sequence is proprietary.
    Database link: Q9Y6A2

  • Positive control

    • WB: Mouse brain whole cell lysate.
  • General notes

     This product was previously labelled as CYP46

     

Properties

Applications

Our Abpromise guarantee covers the use of ab228656 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 57 kDa.

Target

  • Relevance

    The Cyp46 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed exclusively in the brain, where it converts cholesterol to 24S-hydroxycholesterol by adding a hydroxyl group to cholesterol, producing a product that is more soluble than cholesterol and able to be exported from the brain. Cyp46 is also known as 24S-cholesterol hydroxylase
  • Cellular localization

    Endoplasmic reticulum
  • Database links

  • Alternative names

    • Cholesterol 24-hydroxylase antibody
    • CP46 antibody
    • CYP46 antibody
    • CYP46A1 antibody
    • cytochrome P450 family 46 antibody
    see all

Images

  • Anti-CYP46A1 antibody (ab228656) at 1/1000 dilution + Mouse brain whole cell lysate at 50 µg

    Developed using the ECL technique.

    Predicted band size: 57 kDa



    7.5% SDS-PAGE

References

ab228656 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab228656.
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