Overview

  • Product name

    Anti-CYP51A1/CYP51 antibody
    See all CYP51A1/CYP51 primary antibodies
  • Description

    Rabbit polyclonal to CYP51A1/CYP51
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment corresponding to Human CYP51A1/CYP51 aa 300-503 (C terminal).
    Database link: Q16850

  • Positive control

    • WB; Mouse liver, mouse kidney and Rat liver extracts. IHC-P; Mouse kidney tisue. IF; MCF7 cells.
  • General notes

     This product was previously labelled as CYP51A1

     

Applications

Our Abpromise guarantee covers the use of ab210792 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/20 - 1/100.
IHC-P 1/50 - 1/200.
WB 1/500 - 1/2000. Predicted molecular weight: 56 kDa.

Target

  • Function

    Catalyzes C14-demethylation of lanosterol; it transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
  • Tissue specificity

    Ubiquitously expressed with highest levels in testis, ovary, adrenal, prostate, liver, kidney and lung.
  • Pathway

    Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 1/6.
  • Sequence similarities

    Belongs to the cytochrome P450 family.
  • Cellular localization

    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CP51 antibody
    • CP51A_HUMAN antibody
    • CYP51 antibody
    • CYP51A1 antibody
    • CYPL1 antibody
    • CYPLI antibody
    • Cytochrome P450 51 antibody
    • Cytochrome P450 51A1 antibody
    • Cytochrome P450 family 51 subfamily A member 1 antibody
    • Cytochrome P450 family 51 subfamily A polypeptide 1 antibody
    • Cytochrome P450, 51 (lanosterol 14 alpha demethylase) antibody
    • Cytochrome P450-14DM antibody
    • Cytochrome P45014DM antibody
    • Cytochrome P450LI antibody
    • Lanosterol 14-alpha demethylase antibody
    • LDM antibody
    • P450 14DM antibody
    • P450L1 antibody
    • Sterol 14-alpha demethylase antibody
    see all

Images

  • All lanes : Anti-CYP51A1/CYP51 antibody (ab210792) at 1/500 dilution

    Lane 1 : Mouse liver extract
    Lane 2 : Mouse kidney extract
    Lane 3 : Rat liver extract

    Predicted band size: 56 kDa

  • Immunohistochemical analysis of paraffin-embedded mouse kidney tissue labeling CYP51A1/CYP51 with ab210792 at 1/100 dilution.

  • Immunofluorescent analysis of MCF7 cells labeling CYP51A1/CYP51 with ab210792 at 1/20 dilution. Blue: DAPI for nuclear staining.

References

This product has been referenced in:

  • Ge Q  et al. Mulberry Leaf Regulates Differentially Expressed Genes in Diabetic Mice Liver Based on RNA-Seq Analysis. Front Physiol 9:1051 (2018). Read more (PubMed: 30131712) »
See 1 Publication for this product

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