Key features and details
- Potent H1 and 5-HT2B antagonist. Non-selective receptor antagonist.
- CAS Number: 41354-29-4
- Purity: > 99%
- Soluble in water to 10 mM (with warming) and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Product nameCyproheptadine hydrochloride, H1 and 5-HT2B antagonist
DescriptionPotent H1 and 5-HT2B antagonist. Non-selective receptor antagonist.
Potent H1 and 5-HT2B antagonist (Ki and pKi values are 10 and 1.4 nM, respectively). Non-selective receptor antagonist (shows high potency (low nM) at other 5-HT, dopamine and muscarinic acetylcholine receptors. Displays antihistaminergic and antiserotonergic effects.
Chemical name4-(5H-Dibenzo[a,d]cyclohepten-5-ylidine)methylpiperidine hydrochloride sesquihydrate
Storage instructionsStore at Room Temperature. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 10 mM (with warming) and in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120732 has not yet been referenced specifically in any publications.