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Rabbit polyclonal to Cystatin C - C-terminal
Synthetic peptide within Mouse Cystatin C (C terminal). The exact sequence is proprietary. Carrier-protein conjugated.
Database link: P21460
WB: Mouse brain tissue lysate.
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 15 kDa.
As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.
Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.
Involvement in disease
Macular degeneration, age-related, 11
Belongs to the cystatin family.
The Thr-25 variant is O-glycosylated with a core 1 or possibly core 8 glycan. The signal peptide of the O-glycosylated Thr-25 variant is cleaved between Ala-20 and Val-21.
Information by UniProt
AD 8 antibody
Amyloid angiopathy and cerebral hemorrhage antibody
Western blot - Anti-Cystatin C antibody - C-terminal (ab227279)
Anti-Cystatin C antibody - C-terminal (ab227279) at 1/2000 dilution + Mouse brain tissue lysate at 50 µg
Predicted band size:
15% SDS-PAGE gel.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"