Anti-Cystatin SN/CST1 antibody (ab68329)
Key features and details
- Mouse polyclonal to Cystatin SN/CST1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Cystatin SN/CST1 antibody
See all Cystatin SN/CST1 primary antibodies -
Description
Mouse polyclonal to Cystatin SN/CST1 -
Host species
Mouse -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein within Human Cystatin SN/CST1. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements. (NP_001889.2, 1 a.a. ~ 141 a.a)
Database link: NP_001889.2 -
Positive control
- Cystatin SN/CST1 transfected 293T cell lysate
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.40
Constituent: 100% PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab68329 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Detects a band of approximately 13 kDa (predicted molecular weight: 16 kDa).
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Notes |
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WB
1/500 - 1/1000. Detects a band of approximately 13 kDa (predicted molecular weight: 16 kDa). |
Target
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Function
Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well. -
Tissue specificity
Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in saliva, tears, urine and seminal fluid. -
Sequence similarities
Belongs to the cystatin family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 1469 Human
- Omim: 123855 Human
- SwissProt: P01037 Human
- Unigene: 123114 Human
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Alternative names
- CST1 antibody
- Cystain SAI antibody
- Cystain-SA-I antibody
see all
Images
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All lanes : Anti-Cystatin SN/CST1 antibody (ab68329) at 1/500 dilution
Lane 1 : Cystatin SN/CST1 transfected 293T cell lysate
Lane 2 : non transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
All lanes : Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution
Predicted band size: 16 kDa
Observed band size: 13 kDa why is the actual band size different from the predicted?
Datasheets and documents
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Datasheet download
References (1)
ab68329 has been referenced in 1 publication.
- Chen S et al. CST1 Promoted Gastric Cancer Migration and Invasion Through Activating Wnt Pathway. Cancer Manag Res 13:1901-1907 (2021). PubMed: 33658852