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    cytarabine-pyrimidine-nucleoside-analog-ab141924.pdf

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Cell Biology Cell Cycle Cell Cycle Inhibitors p53
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Cytarabine, Pyrimidine nucleoside analog (ab141924)

  • Datasheet
  • SDS
  • COA
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Chemical Structure - Cytarabine, Pyrimidine nucleoside analog (ab141924)

    Key features and details

    • Pyrimidine nucleoside analog
    • CAS Number: 147-94-4
    • Purity: > 99%
    • Soluble in water to 100 mM and in DMSO to 50 mM
    • Form / State: Solid
    • Source: Synthetic

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    Overview

    • Product name

      Cytarabine, Pyrimidine nucleoside analog
    • Description

      Pyrimidine nucleoside analog
    • Biological description

      Pyrimidine nucleoside analog able to inhibits DNA synthesis. Active specifically on the S phase of the cell cycle. Chemotherapeutic agent. Antiviral and immunosuppressant properties.

    • Purity

      > 99%
    • CAS Number

      147-94-4
    • Chemical structure

      Chemical Structure

    Properties

    • Chemical name

      4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone
    • Molecular weight

      243.22
    • Molecular formula

      C9H13N3O5
    • PubChem identifier

      6253
    • Storage instructions

      Store at Room Temperature. The product can be stored for up to 12 months.
    • Solubility overview

      Soluble in water to 100 mM and in DMSO to 50 mM
    • Handling

      Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

      Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

    • SMILES

      C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O
    • Source

      Synthetic

    • Research areas

      • Cell Biology
      • Cell Cycle
      • Cell Cycle Inhibitors
      • p53
      • Cell Biology
      • Apoptosis
      • Intracellular
      • p53 Pathway
      • Epigenetics and Nuclear Signaling
      • Chromatin Modifying Enzymes
      • Acetylation
      • Epigenetics and Nuclear Signaling
      • DNA / RNA
      • DNA Damage & Repair
      • DNA Damage Response
      • p53
      • Epigenetics and Nuclear Signaling
      • DNA / RNA
      • DNA Synthesis
      • Topoisomerases
      • Epigenetics and Nuclear Signaling
      • DNA / RNA
      • DNA Synthesis
      • Other
      • Signal Transduction
      • Signaling Pathway
      • Nuclear Signaling
      • Nuclear Hormone Receptors
      • Testosterone
      • Signal Transduction
      • Growth Factors/Hormones
      • Hormones
      • Signal Transduction
      • Signaling Pathway
      • Nuclear Signaling
      • Nuclear Hormone Receptors
      • Co-activators/co-repressors
      • Epigenetics and Nuclear Signaling
      • Transcription
      • Cancer susceptibility
      • Tumor Suppressors
      • Epigenetics and Nuclear Signaling
      • Nuclear Signaling Pathways
      • Nuclear Receptors
      • Co-activators/co-repressors
      • Epigenetics and Nuclear Signaling
      • Nuclear Signaling Pathways
      • Nuclear Receptors
      • Corticoid
      • Epigenetics and Nuclear Signaling
      • Nuclear Signaling Pathways
      • Nuclear Receptors
      • Retinoic & Retinoid
      • Epigenetics and Nuclear Signaling
      • Nuclear Signaling Pathways
      • Nuclear Receptors
      • Testosterone
      • Epigenetics and Nuclear Signaling
      • Cell cycle
      • Cell Cycle Inhibitors
      • p53
      • Epigenetics and Nuclear Signaling
      • Transcription
      • Transcription Factors
      • Epigenetics and Nuclear Signaling
      • Nuclear Signaling Pathways
      • Nuclear Receptors
      • Orphan Nuclear Receptors
      • Signal Transduction
      • Metabolism
      • Drug metabolism
      • Epigenetics and Nuclear Signaling
      • Chromatin Modifying Enzymes
      • Acetylation
      • HAT
      • Cancer
      • Cell cycle
      • Cell cycle inhibitors
      • p53 pathway
      • Cancer
      • Signal transduction
      • Nuclear signaling
      • Nuclear hormone receptors
      • Coactivators and repressors
      • Cancer
      • Signal transduction
      • Nuclear signaling
      • Nuclear hormone receptors
      • Other
      • Cancer
      • Oncoproteins/suppressors
      • Tumor suppressors
      • p53 pathway
      • Developmental Biology
      • Reproduction
      • Hormones
      • Cancer
      • Cancer Metabolism
      • Metabolic signaling pathway
      • Metabolism of lipids and lipoproteins
      • Biochemicals
      • Product Range
      • Just Add Water
      • Biochemicals
      • Chemical Type
      • Biochemicals
      • Biochemicals
      • Pharmacology
      • Signaling
      • Apoptosis & cell cycle
      • Other
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Lipid and lipoprotein metabolism
      • Lipid metabolism
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Nucleotide metabolism
      • Purine and pyrimidine synthesis
      • Metabolism
      • Pathways and Processes
      • Metabolic signaling pathways
      • Drug metabolism
      • Metabolism
      • Types of disease
      • Obesity
      • Biochemicals
      • Research Area
      • Cancer
      • Apoptosis & cell cycle
      • Other
      • Biochemicals
      • Pharmacology
      • Signaling
      • DNA, RNA & protein synthesis
      • DNA & RNA synthesis
      • Biochemicals
      • Research Area
      • Cancer
      • DNA, RNA & protein synthesis
      • DNA & RNA synthesis
      • Biochemicals
      • Pharmacology
      • Signaling
      • Immunomodulators
      • Immunomodulators & Immunosuppressants
      • Biochemicals
      • Pharmacology
      • Signaling
      • Immunomodulators
      • Antiviral

    Associated products

    • Related Products

      • ioGlutamatergic Neurons – Human iPSC-Derived Glutamatergic Neurons (ab259259)

    Images

    • Chemical Structure - Cytarabine, Pyrimidine nucleoside analog (ab141924)
      Chemical Structure - Cytarabine, Pyrimidine nucleoside analog (ab141924)
      2D chemical structure image of ab141924, Cytarabine, Pyrimidine nucleoside analog

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download
    • COA

    References (1)

    Publishing research using ab141924? Please let us know so that we can cite the reference in this datasheet.

    ab141924 has been referenced in 1 publication.

    • Lautenschläger J  et al. An Easy-to-Implement Protocol for Preparing Postnatal Ventral Mesencephalic Cultures. Front Cell Neurosci 12:44 (2018). PubMed: 29556177

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