Cytarabine, Pyrimidine nucleoside analog (ab141924)
- Datasheet
- References (1)
Overview
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Product name
Cytarabine, Pyrimidine nucleoside analog -
Description
Pyrimidine nucleoside analog -
Biological description
Pyrimidine nucleoside analog able to inhibits DNA synthesis. Active specifically on the S phase of the cell cycle. Chemotherapeutic agent. Antiviral and immunosuppressant properties. -
Purity
> 99% -
CAS Number
147-94-4 -
Chemical structure
Properties
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Chemical name
4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone -
Molecular weight
243.22 -
Molecular formula
C9H13N3O5 -
PubChem identifier
6253 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM and in DMSO to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O -
Source
Synthetic
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Research areas
References
This product has been referenced in:
- Sharma P et al. Synthesis of cytarabine lipid drug conjugate for treatment of meningeal leukemia: development, characterization and in vitro cell line studies. J Biomed Nanotechnol 8:928-37 (2012). Read more (PubMed: 23030001) »
- Sampath D et al. Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial. Blood 107:2517-24 (2006). Read more (PubMed: 16293603) »
- Hamada A et al. Clinical pharmacokinetics of cytarabine formulations. Clin Pharmacokinet 41:705-18 (2002). Read more (PubMed: 12162758) »
