Anti-Cytochrome b5 antibody (ab186863)

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Key features and details

  • Rabbit polyclonal to Cytochrome b5
  • Suitable for: WB
  • Reacts with: Mouse, Rat, Human
  • Isotype: IgG

Overview

  • Product name

    Anti-Cytochrome b5 antibody
    See all Cytochrome b5 primary antibodies

  • Description

    Rabbit polyclonal to Cytochrome b5

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details

  • Species reactivity

    Reacts with: Mouse, Rat, Human

  • Immunogen

    Recombinant fragment corresponding to Human Cytochrome b5 aa 1-100 (N terminal).
    Database link: P00167

  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

Applications

Our Abpromise guarantee covers the use of ab186863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 15 kDa.

Target

  • Function

    Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.

  • Involvement in disease

    Defects in CYB5A are the cause of methemoglobinemia CYB5A-related (METHB-CYB5A) [MIM:250790]. A form of methemoglobinemia, a hematologic disease characterized by the presence of excessive amounts of methemoglobin in blood cells, resulting in decreased oxygen carrying capacity of the blood, cyanosis and hypoxia.

  • Sequence similarities

    Belongs to the cytochrome b5 family.
    Contains 1 cytochrome b5 heme-binding domain.

  • Cellular localization

    Cytoplasm and Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt

  • Database links

    see all

  • Alternative names

    • CYB 5 antibody
    • CYB 5A antibody
    • CYB5 antibody
    • CYB5_HUMAN antibody
    • Cyb5a antibody
    • Cytochrome b 5 antibody
    • Cytochrome b5 (microsomal) antibody
    • Cytochrome b5 antibody
    • Cytochrome b5 type A (microsomal) antibody
    • Cytochrome b5 type A antibody
    • MCB 5 antibody
    • MCB5 antibody
    • Microsomal cytochrome b5 antibody
    • Microsomal cytochrome b5 type A antibody
    • Type 1 cyt b5 antibody
    see all

Images

  • Western blot - Anti-Cytochrome b5 antibody (ab186863)
    Western blot - Anti-Cytochrome b5 antibody (ab186863)
    All lanes : Anti-Cytochrome b5 antibody (ab186863) at 1/500 dilution

    Lane 1 : MCF7 cell extract
    Lane 2 : A549 cell extract
    Lane 3 : HT29 cell extract
    Lane 4 : 293T cell extract
    Lane 5 : M21 cell extract

    Predicted band size: 15 kDa

References (0)

Publishing research using ab186863? Please let us know so that we can cite the reference in this datasheet.

ab186863 has not yet been referenced specifically in any publications.

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