Anti-Cytochrome b5 antibody (ab23852)
- Datasheet
- References (2)
- Protocols
Overview
-
Product nameAnti-Cytochrome b5 antibody
See all Cytochrome b5 primary antibodies -
DescriptionGoat polyclonal to Cytochrome b5
-
Host speciesGoat
-
SpecificityNon-specific cross-reactivity with 50 and 60 kDa species.
-
Tested applicationsSuitable for: WBmore details
-
Species reactivityReacts with: Rat, Rabbit, Human
-
Immunogen
Full length native protein (purified) (Rabbit).
Properties
-
FormLiquid
-
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
-
Storage bufferPreservative: 0.05% Sodium azide
-
PurityWhole antiserum
-
ClonalityPolyclonal
-
IsotypeIgG
-
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
Our Abpromise guarantee covers the use of ab23852 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | 1/1000. Predicted molecular weight: 15 kDa. |
Target
-
FunctionCytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound oxygenases.
-
Involvement in diseaseDefects in CYB5A are the cause of methemoglobinemia CYB5A-related (METHB-CYB5A) [MIM:250790]. A form of methemoglobinemia, a hematologic disease characterized by the presence of excessive amounts of methemoglobin in blood cells, resulting in decreased oxygen carrying capacity of the blood, cyanosis and hypoxia.
-
Sequence similaritiesBelongs to the cytochrome b5 family.
Contains 1 cytochrome b5 heme-binding domain. -
Cellular localizationCytoplasm and Endoplasmic reticulum membrane. Microsome membrane.
- Information by UniProt
-
Database links
- Entrez Gene: 1528 Human
- Entrez Gene: 64001 Rat
- Omim: 613218 Human
- SwissProt: P00167 Human
- SwissProt: P00173 Rat
- Unigene: 465413 Human
- Unigene: 1055 Rat
-
Alternative names
- CYB 5 antibody
- CYB 5A antibody
- CYB5 antibody
see all
Protocols
Datasheets and documents
References
This product has been referenced in:
- Samhan-Arias AK et al. Stimulation and clustering of cytochrome b(5) reductase in caveolin-rich lipid microdomains is an early event in oxidative stress-mediated apoptosis of cerebellar granule neurons. J Proteomics : (2011). WB . Read more (PubMed: 22200675) »
- Samhan-Arias AK et al. Clustering of plasma membrane-bound cytochrome b5 reductase within 'lipid raft' microdomains of the neuronal plasma membrane. Mol Cell Neurosci 40:14-26 (2009). Rat . Read more (PubMed: 18973815) »