Key features and details
- Rabbit polyclonal to Cytochrome P450 1A1 + 1A2
- Suitable for: ELISA, WB
- Reacts with: Rainbow trout
- Isotype: IgG
Product nameAnti-Cytochrome P450 1A1 + 1A2 antibody
See all Cytochrome P450 1A1 + 1A2 primary antibodies
DescriptionRabbit polyclonal to Cytochrome P450 1A1 + 1A2
Tested applicationsSuitable for: ELISA, WBmore details
Species reactivityReacts with: Rainbow trout
- Liver microsomes from beta naphtoflavone treated (BNF), benzo(a)pyrene treated (BaP).
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.1% Sodium azide
Constituents: 1% BSA, 0.87% Sodium chloride, 1.64% Sodium phosphate
Concentration information loading...
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
Our Abpromise guarantee covers the use of ab37131 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||1/100 - 1/2000.
The antibody is dissolved in a buffer containing BSA, and is therefore not recommended to use for coating.
|WB||1/100 - 1/2000. Predicted molecular weight: 55 kDa.|
RelevanceCytochrome P450 oxidase (commonly abbreviated CYP) is a generic term for a large number of related, but distinct, oxidative enzymes important in vertebrate physiology. The cytochrome P450 mixed-function monooxygenase system is probably the most important element of Phase I metabolism in mammals. P450s are membrane-bound, either in the inner membrane of mitochondria or in the endoplasmic reticulum of cells where they metabolise thousands of endogenous and exogenous compounds. In the liver, these substrates include toxins, drugs, and other unneeded and potentially harmful molecules. Humans have 18 families of cytochrome P450 genes and 43 subfamilies; the CYP1 family is involved in drug metabolism and includes 3 subfamilies, 3 genes and 1 pseudogene.
Cellular localizationEndoplasmic reticulum
- Aryl hydrocarbon hydroxylase antibody
- CP11 antibody
- CP12 antibody
ab37131 has been referenced in 1 publication.
- Espe M & Holen E Taurine attenuates apoptosis in primary liver cells isolated from Atlantic salmon (Salmo salar). Br J Nutr 110:20-8 (2013). WB ; Fish . PubMed: 23182339