Product nameAnti-Cytochrome P450 2A6 antibody [F16 P2 D8]
See all Cytochrome P450 2A6 primary antibodies
DescriptionMouse monoclonal [F16 P2 D8] to Cytochrome P450 2A6
Tested applicationsSuitable for: WB, ELISA, IHC-P, ICC/IFmore details
Species reactivityReacts with: Human
Synthetic peptide derived from the C-terminus of human CYP2A6 and conjugated to ovalbumin.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.08% Sodium azide
Concentration information loading...
PurityProtein G purified
Clone numberF16 P2 D8
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
Our Abpromise guarantee covers the use of ab56069 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 54 kDa (predicted molecular weight: 57 kDa).|
|ELISA||Use at an assay dependent concentration.|
|IHC-P||Use a concentration of 1 µg/ml.|
|ICC/IF||Use at an assay dependent concentration.|
FunctionExhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Possesses low phenacetin O-deethylation activity.
Sequence similaritiesBelongs to the cytochrome P450 family.
Cellular localizationEndoplasmic reticulum membrane. Microsome membrane.
- Information by UniProt
- Coumarin 7 hydroxylase antibody
- Coumarin 7-hydroxylase antibody
- CP2A6_HUMAN antibody
Anti-Cytochrome P450 2A6 antibody [F16 P2 D8] (ab56069) at 1 µg/ml
Predicted band size: 57 kDa
Observed band size: 54 kDa why is the actual band size different from the predicted?
This image shows normal human liver tissue stained by ab56069 at 1µg/ml.
This product has been referenced in:
- Dhamankar V et al. Gene expression and immunochemical localization of major cytochrome P450 drug-metabolizing enzymes in bovine nasal olfactory and respiratory mucosa. Inhal Toxicol 27:767-77 (2015). Read more (PubMed: 26572092) »