Overview

  • Product name

    Anti-Cytochrome P450 2B6/CYP2B6 antibody
    See all Cytochrome P450 2B6/CYP2B6 primary antibodies
  • Description

    Rabbit polyclonal to Cytochrome P450 2B6/CYP2B6
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human Cytochrome P450 2B6/CYP2B6 (internal sequence). NP_000758.
    Database link: P20813

  • Positive control

    • Human colon cancer tissue lysate and Human gastric cancer tissue.
  • General notes

     This product was previously labelled as Cytochrome P450 2B6

     

Properties

Applications

Our Abpromise guarantee covers the use of ab198870 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/25 - 1/100.
WB 1/200 - 1/1000. Predicted molecular weight: 56 kDa.

Target

  • Function

    Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
  • Tissue specificity

    Expressed in liver, lung and heart right ventricle.
  • Sequence similarities

    Belongs to the cytochrome P450 family.
  • Post-translational
    modifications

    Phosphorylation is accompanied by a decrease in enzyme activity.
  • Cellular localization

    Endoplasmic reticulum membrane. Microsome membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • 1,4 cineole 2 exo monooxygenase antibody
    • 11B1 antibody
    • CP2B6_HUMAN antibody
    • CPB 6 antibody
    • CPB6 antibody
    • CYP 2B6 antibody
    • CYP IIB6 antibody
    • CYP2B antibody
    • CYP2B6 antibody
    • CYP2B7 antibody
    • CYP2B7P antibody
    • CYPIIB6 antibody
    • Cytochrome P450 2B6 antibody
    • Cytochrome P450 family 2 subfamily B antibody
    • Cytochrome P450 family 2 subfamily B polypeptide 6 antibody
    • Cytochrome P450 IIB1 antibody
    • Cytochrome P450 phenobarbital inducible antibody
    • Cytochrome P450 subfamily IIB (phenobarbital inducible) antibody
    • Cytochrome P450 subfamily IIB (phenobarbital inducible) polypeptide 6 antibody
    • Cytochrome P450 subfamily IIB polypeptide 6 antibody
    • EFVM antibody
    • IIB1 antibody
    • P450 antibody
    • P450 IIB1 antibody
    • P450IIB1 antibody
    see all

Images

  • Anti-Cytochrome P450 2B6/CYP2B6 antibody (ab198870) at 1/400 dilution + Human colon cancer tissue lysate at 40 µg

    Predicted band size: 56 kDa


    Exposure time: 4 minutes


    Gel: 8% SDS-PAGE

  • Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue labeling Cytochrome P450 2B6/CYP2B6 with ab198870 at 1/25 dilution.

References

ab198870 has not yet been referenced specifically in any publications.

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