Product nameAnti-Cytokeratin 19 antibody
See all Cytokeratin 19 primary antibodies
DescriptionGuinea pig polyclonal to Cytokeratin 19
Host speciesGuinea pig
Tested applicationsSuitable for: IHC-Fr, WB, IHC-P, ICC/IFmore details
Species reactivityReacts with: Cow, Human
Predicted to work with: OrangutanDoes not react with: Mouse, Rat
Recombinant full length protein corresponding to Human Cytokeratin 19 aa 1-400. (Purified from MCF-7 cells).
MTSYSYRQSSATSSFGGLGGGSVRFGPGVAFRAPSIHGGSGGRGVSVSSA RFVSSSSSGAYGGGYGGVLTASDGLLAGNEKLTMQNLNDRLASYLDKVRA LEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDKILGATIENSR IVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDL EMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILS DMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLR RTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLG DVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQEDHYNNLSASKVL
Database link: P08727
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.09% Sodium azide
Constituent: 0.5% BSA
Our Abpromise guarantee covers the use of ab192751 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/3000. Predicted molecular weight: 44 kDa.
FunctionInvolved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Tissue specificityExpressed in a defined zone of basal keratinocytes in the deep outer root sheath of hair follicles. Also observed in sweat gland and mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, ectocervical epithelium (at protein level). Expressed in epidermal basal cells, in nipple epidermis and a defined region of the hair follicle. Also seen in a subset of vascular wall cells in both the veins and artery of human umbilical cord, and in umbilical cord vascular smooth muscle. Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma in structures that contain dystrophin and spectrin.
Sequence similaritiesBelongs to the intermediate filament family.
Developmental stagePresent in hair follicles at all stages of development.
DomainThis keratin differs from all other IF proteins in lacking the C-terminal tail domain.
- Information by UniProt
- 40 kDa keratin intermediate filament antibody
- CK 19 antibody
- CK-19 antibody
ab192751 has not yet been referenced specifically in any publications.