• Product name

    Anti-Cytokeratin 4 antibody
    See all Cytokeratin 4 primary antibodies
  • Description

    Rabbit polyclonal to Cytokeratin 4
  • Host species

  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Fusion protein within Human Cytokeratin 4 (internal sequence). The exact sequence is proprietary. (BC042174) The identity of the protein fusion partner is GST.
    Database link: P19013

  • Positive control

    • Human liver cancer tissue lysate and Human cervical cancer tissue.



Our Abpromise guarantee covers the use of ab197385 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/5 - 1/20.
WB 1/500 - 1/2000. Predicted molecular weight: 57 kDa.


  • Tissue specificity

    Detected in the suprabasal layer of the stratified epithelium of the esophagus, exocervix, vagina, mouth and lingual mucosa, and in cells and cell clusters in the mucosa and serous gland ducts of the esophageal submucosa (at protein level). Expressed widely in the exocervix and esophageal epithelium, with lowest levels detected in the basal cell layer.
  • Involvement in disease

    Defects in KRT4 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.
  • Sequence similarities

    Belongs to the intermediate filament family.
  • Information by UniProt
  • Database links

  • Form

    Localisation: Intermediate filament (Cytoskeleton).
  • Alternative names

    • CK 4 antibody
    • CK-4 antibody
    • CK4 antibody
    • CYK4 antibody
    • Cytokeratin 4 antibody
    • Cytokeratin-4 antibody
    • Cytokeratin4 antibody
    • FLJ31692 antibody
    • K2C4_HUMAN antibody
    • K4 antibody
    • Keratin 4 antibody
    • Keratin antibody
    • Keratin type II cytoskeletal 4 antibody
    • Keratin-4 antibody
    • Keratin4 antibody
    • KRT 4 antibody
    • Krt4 antibody
    • type II cytoskeletal 4 antibody
    • Type-II keratin Kb4 antibody
    see all


  • Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue labeling Cytokeratin 4 with ab197385 at 1/10 dilution.

  • Anti-Cytokeratin 4 antibody (ab197385) at 1/200 dilution + Human liver cancer tissue at 40 µg

    Predicted band size: 57 kDa

    Exposure time: 1 minute

    8% SDS-PAGE


ab197385 has not yet been referenced specifically in any publications.

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