Key features and details
- Rabbit polyclonal to Cytokeratin 6a
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-Cytokeratin 6a antibody
See all Cytokeratin 6a primary antibodies
DescriptionRabbit polyclonal to Cytokeratin 6a
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Human
Does not react with: Rat
Synthetic peptide within Human Cytokeratin 6a aa 1-100 (N terminal). The exact sequence is proprietary.
(Peptide available as
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab52869 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500. Detects a band of approximately 56 kDa (predicted molecular weight: 60 kDa).|
Tissue specificityConstitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath.
Involvement in diseaseDefects in KRT6A are a cause of pachyonychia congenita type 1 (PC1) [MIM:167200]; also known as Jadassohn-Lewandowsky syndrome. PC1 is an autosomal dominant ectodermal dysplasia characterized by hypertrophic nail dystrophy resulting in onchyogryposis (thickening and increase in curvature of the nail), palmoplantar keratoderma, follicular hyperkeratosis, and oral leukokeratosis. Hyperhidrosis of the hands and feet is usually present.
Sequence similaritiesBelongs to the intermediate filament family.
- Information by UniProt
- CK-6A antibody
- CK-6D antibody
- CK6A antibody
Anti-Cytokeratin 6a antibody (ab52869) at 1/500 dilution + A431 cell lysate at 10 µg
Goat anti-rabbit HRP at 1/2000 dilution
Predicted band size: 60 kDa
Observed band size: 56 kDa why is the actual band size different from the predicted?
ab52869 has not yet been referenced specifically in any publications.