Overview

  • Product name

    Anti-Cytokeratin 6a antibody [KRT6/1702] - BSA and Azide free
    See all Cytokeratin 6a primary antibodies
  • Description

    Mouse monoclonal [KRT6/1702] to Cytokeratin 6a - BSA and Azide free
  • Host species

    Mouse
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Recombinant full length protein corresponding to Human Cytokeratin 6a aa 1-564.
    Database link: P02538

  • Positive control

    • Human bladder carcinoma tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Constituent: 100% PBS
  • Concentration information loading...
  • Purity

    Protein A purified
  • Purification notes

    ab218899 was purified from Bioreactor Concentrate by Protein A/G.
  • Clonality

    Monoclonal
  • Clone number

    KRT6/1702
  • Isotype

    IgG2a
  • Light chain type

    kappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab218899 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 0.1 - 0.2 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

(Primary incubation for 30 minutes at RT).

Target

  • Tissue specificity

    Constitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath.
  • Involvement in disease

    Defects in KRT6A are a cause of pachyonychia congenita type 1 (PC1) [MIM:167200]; also known as Jadassohn-Lewandowsky syndrome. PC1 is an autosomal dominant ectodermal dysplasia characterized by hypertrophic nail dystrophy resulting in onchyogryposis (thickening and increase in curvature of the nail), palmoplantar keratoderma, follicular hyperkeratosis, and oral leukokeratosis. Hyperhidrosis of the hands and feet is usually present.
  • Sequence similarities

    Belongs to the intermediate filament family.
  • Information by UniProt
  • Database links

  • Alternative names

    • CK-6A antibody
    • CK-6D antibody
    • CK6A antibody
    • CK6C antibody
    • CK6D antibody
    • Cytokeratin-6A antibody
    • Cytokeratin-6D antibody
    • K2C6A_HUMAN antibody
    • K6A antibody
    • K6C antibody
    • K6D antibody
    • keratin 6A antibody
    • Keratin antibody
    • Keratin, type II cytoskeletal 6A antibody
    • Keratin-6A antibody
    • Krt6a antibody
    • KRT6C antibody
    • KRT6D antibody
    • type II cytoskeletal 6A antibody
    • Type-II keratin Kb6 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human bladder carcinoma tissue labeling Cytokeratin 6 with ab218899 at 0.2 µg/mL. 

References

ab218899 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab218899.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up