Key features and details
- Goat polyclonal to Cytomegalovirus AD169 (HRP)
- Suitable for: WB, ELISA, IHC-Fr
- Conjugation: HRP
- Isotype: IgG
Product nameAnti-Cytomegalovirus AD169 antibody (HRP)
See all Cytomegalovirus AD169 primary antibodies
DescriptionGoat polyclonal to Cytomegalovirus AD169 (HRP)
SpecificityThis antibody reacts with Cytomegalovirus AD 169 in viral and infected tissue samples.
Tested applicationsSuitable for: WB, ELISA, IHC-Frmore details
Species reactivityReacts with: Other species
Purified virions of Cytomegalovirus strain AD 169 (gB antigen).
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferPreservative: 0.002% Thimerosal (merthiolate)
Constituents: 1% BSA, PBS
Concentration information loading...
- TMB ELISA Substrate (Highest Sensitivity) (ab171522)
- TMB ELISA Substrate (High Sensitivity) (ab171523)
- TMB ELISA Substrate (Fast Kinetic Rate) (ab171524)
- TMB ELISA Substrate (Slow Kinetic Rate) (ab171525)
- TMB ELISA Substrate (Slower Kinetic Rate) (ab171526)
- TMB ELISA Substrate (Slowest Kinetic Rate) (ab171527)
- 450 nm Stop Solution for TMB Substrate (ab171529)
- 650 nm Stop Solution for TMB Substrate (ab171531)
- Immunoassay Blocking Buffer (ab171534)
- Immunoassay Blocking (BSA Free) (ab171535)
Our Abpromise guarantee covers the use of ab69245 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
RelevanceCytomegalovirus (CMV) is a member of the Herpes virus family. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid which is embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope that is decorated with virus-specific glycoprotein spikes. The viral genes are co-ordinately expressed in groups at various times after infection. Early viral proteins are expressed in the nucleus of infected cells within 3 to 24 hours of infection prior to the commencement of viral DNA replication. This is followed by expression of the early intermediate genes, which encode enzymes required for viral DNA replication. After 48 to 72 hours, a number of late viral antigens may be demonstrated in the nuclei and cytoplasm of infected cells. Cytomegalovirus strain AD169 is a laboratory-adapted strain and appears to lack a 15kb region of the 200kb genome that is present in clinical isolates. This region contains 19 open reading frames whose functions have yet to be elucidated. AD169 is also unique in that it is unable to enter latency and nearly always assumes lytic growth upon infection.
- HCMV antibody
- HHV5 antibody
- Human Herpesvirus 5 antibody
- UL55 (strain AD169) antibody
ab69245 has been referenced in 1 publication.
- Pires F et al. A rapid magnetic particle-based enzyme immunoassay for human cytomegalovirus glycoprotein B quantification. J Pharm Biomed Anal 156:372-378 (2018). PubMed: 29758495