Overview

  • Product name

    Anti-Cytomegalovirus AD169 antibody (HRP)
    See all Cytomegalovirus AD169 primary antibodies
  • Description

    Goat polyclonal to Cytomegalovirus AD169 (HRP)
  • Host species

    Goat
  • Conjugation

    HRP
  • Specificity

    This antibody reacts with Cytomegalovirus AD 169 in viral and infected tissue samples.
  • Tested applications

    Suitable for: WB, ELISA, IHC-Frmore details
  • Species reactivity

    Reacts with: Other species
  • Immunogen

    Purified virions of Cytomegalovirus strain AD 169 (gB antigen).

Properties

Applications

Our Abpromise guarantee covers the use of ab69245 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/20.
ELISA 1/200.
IHC-Fr 1/20.

Target

  • Relevance

    Cytomegalovirus (CMV) is a member of the Herpes virus family. Members of this family have a characteristic virion structure. The double stranded DNA genome is contained within an icosahedral capsid which is embedded in a proteinaceous layer (tegument) and surrounded by a lipid envelope that is decorated with virus-specific glycoprotein spikes. The viral genes are co-ordinately expressed in groups at various times after infection. Early viral proteins are expressed in the nucleus of infected cells within 3 to 24 hours of infection prior to the commencement of viral DNA replication. This is followed by expression of the early intermediate genes, which encode enzymes required for viral DNA replication. After 48 to 72 hours, a number of late viral antigens may be demonstrated in the nuclei and cytoplasm of infected cells. Cytomegalovirus strain AD169 is a laboratory-adapted strain and appears to lack a 15kb region of the 200kb genome that is present in clinical isolates. This region contains 19 open reading frames whose functions have yet to be elucidated. AD169 is also unique in that it is unable to enter latency and nearly always assumes lytic growth upon infection.
  • Alternative names

    • HCMV antibody
    • HHV5 antibody
    • Human Herpesvirus 5 antibody
    • UL55 (strain AD169) antibody

References

This product has been referenced in:

  • Pires F  et al. A rapid magnetic particle-based enzyme immunoassay for human cytomegalovirus glycoprotein B quantification. J Pharm Biomed Anal 156:372-378 (2018). Read more (PubMed: 29758495) »
See 1 Publication for this product

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