Overview

  • Product name

  • Description

    Rabbit polyclonal to D-10
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide corresponding to Human D-10 (internal sequence).
    Database link: Q494W8

  • Positive control

    • Mouse liver tissue lysate and Human liver cancer tissue.
  • General notes

     This product was previously labelled as CHRFAM7A

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.05% Sodium azide
    Constituents: 49% PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab198719 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 46 kDa.
IHC-P 1/25 - 1/100.

Target

  • Relevance

    The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. CHRFAM7A is encoded by a hybrid gene consisting of a duplication of exons 5 through 10 of the CHRNA7 gene fused 3-prime to a copy of the FAM7A gene (exons A through E). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel.
  • Cellular localization

    Membrane; Multi-pass membrane protein.
  • Database links

  • Alternative names

    • Alpha 7 neuronal nicotinic acetylcholine receptor FAM7A hybrid antibody
    • CHRNA7 (cholinergic receptor nicotinic alpha 7 exons 5 10) and FAM7A (family with sequence similarity 7A exons A E) fusion antibody
    • CHRNA7 antibody
    • CHRNA7 DR1 antibody
    • CHRNA7 FAM7A fusion antibody
    • CHRNA7 FAM7A fusion protein antibody
    • D 10 antibody
    • D-10 antibody
    • D10 antibody
    • MGC120482 antibody
    • MGC120483 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling D-10 with ab198719 at 1/40 dilution.

  • Anti-D-10 antibody (ab198719) at 1/700 dilution + Mouse liver tissue lysate at 40 µg

    Predicted band size: 46 kDa


    Exposure time: 2 minutes


    Gel: 10% SDS-PAGE

References

ab198719 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab198719.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up