Overview

  • Product name

    Anti-D Amino Acid Oxidase antibody
    See all D Amino Acid Oxidase primary antibodies
  • Description

    Rabbit polyclonal to D Amino Acid Oxidase
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant full length protein corresponding to Human D Amino Acid Oxidase.
    Database link: P14920

  • Positive control

    • Raji, HT29 and U87 cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab187525 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 39 kDa.

Target

  • Function

    Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
  • Sequence similarities

    Belongs to the DAMOX/DASOX family.
  • Cellular localization

    Peroxisome.
  • Information by UniProt
  • Database links

  • Alternative names

    • D-amino-acid oxidase antibody
    • DAAO antibody
    • DAMOX antibody
    • DAO antibody
    • DAO1 antibody
    • EC 1.4.3.3 antibody
    • MGC35381 antibody
    • OXDA antibody
    • OXDA_HUMAN antibody
    see all

References

ab187525 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Application
Immunohistochemistry (PFA perfusion fixed frozen sections)
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 2% · Temperature: 23°C
Antigen retrieval step
None
Sample
Mouse Tissue sections (Brain)
Specification
Brain
Permeabilization
Yes - Triton 0.05%
Fixative
Formaldehyde

Abcam user community

Verified customer

Submitted Jan 20 2015

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