• Product name
    Anti-D-Dimer antibody [DD1]
  • Description
    Mouse monoclonal [DD1] to D-Dimer
  • Host species
  • Specificity
    ab10050 is specific for D-Dimer and high molecular weight fibrin degradation products. No cross-reaction with D-Monomer or D-Dimer treated with mercaptoethanol.
  • Tested applications
    Suitable for: ELISA, WB, Sandwich ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    This clone has been derived from hybridization of Sp 2/0 myeloma cells with spleen cells of Balb/c mice immunized with homogenized fibrin clot.

  • General notes

    Concentration varies from lot to lot and can be provided on request.



  • Form
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • Purity
  • Purification notes
    Purified from ascites.
  • Clonality
  • Clone number
  • Myeloma
  • Isotype
  • Research areas


Our Abpromise guarantee covers the use of ab10050 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.
WB Use at an assay dependent dilution.
To be analyzed in sandwich immunoassay, plasma must be diluted with 10 mM Tris/HCl buffer, pH 7.5, containing 1 M NaCl and 0.1 % Tween 20. To avoid non-specific binding, the final NaCl concentration in plasma samples must be 0.5 M or more.
Sandwich ELISA Use at an assay dependent dilution. Can be used as Capture antibody. Recommended for D-Dimer detection in Human Plasma.


  • Relevance
    A fibrin degradation fragment or product that is produced by the action of plasmin on fibrin in the clot dissolution process.
  • Alternative names
    • D Dimer antibody


  • D-Dimer, D-monomer and fibrinogen immunodetection by ab10050 by Western blot:

    Lane 1 - D-Dimer
    Lane 2 - D-monomer
    Lane 3 - fibrinogen
    Lane 4 - D-Dimer treated with mercaptoethanol

    D-Dimer, D-monomer and fibrinogen immunodetection by ab10050 by Western blot:

    Lane 1 - D-Dimer
    Lane 2 - D-


This product has been referenced in:
  • Anderson N  et al. Protein biomarkers in exfoliated cells collected from the human rectal mucosa: implications for colorectal disease detection and monitoring. Int J Colorectal Dis 26:1287-97 (2011). ELISA ; Human . Read more (PubMed: 21698353) »
  • Gulla KC  et al. Activation of mannan-binding lectin-associated serine proteases leads to generation of a fibrin clot. Immunology 129:482-95 (2010). Read more (PubMed: 20002787) »
See all 4 Publications for this product

Customer reviews and Q&As

1-3 of 3 Abreviews or Q&A


Thank you for contacting us.

The quick way to check if a monoclonal is affected by conjugation is to search for commercially available conjugated versions online. I see that both the DD1 and DD5 clones are available biotinylated, though not from Abcam. So, it is likely that biotinylating ab10050 and ab38056 will have no effect on their ability to recognize their targets.

Other than this, I do not know of a way to predict the effect of biotinylation or other conjugation on an antibody's efficacy.

I hope this helps. Please do not hesitate to contact us if you need any more advice or information

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Gracias por tu respuesta.
Lamentablemente la secuencia del epítopo no se ha mapeado, y no disponemos de esta información.
Respecto al clon DD93, probablemente a partir de la semana que viene esté disponible en el catálogo. Si te interesa puedo avisarte cuando esto ocurra.
Si necesitas cualquier otra información, por favor, no dudes en contactarnos de nuevo.

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Thank you for your enquiry. All the information we have on species cross reactivity is specified on the datasheet, these are updated as soon as any new information is brought to our attention. As far as we are aware, cross reactivity with mouse has not yet been tested for use with ab10050. Should you decide to go ahead and purchase this product, please let us know how you get on by submitting an Abreview and in return we will award you 50 Abcam Points, which can be redeemed on a number of rewards (a further 100 points will be offered for an image). Please let me know if you require any further assistance.

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