D-Luciferin, chemiluminescent luciferase substrate (ab143654)

Overview

  • Product name

    D-Luciferin, chemiluminescent luciferase substrate
  • Description

    Cell-permeable chemiluminescent luciferase substrate
  • Biological description

    Cell-permeable chemiluminescent luciferase substrate. Emits lights upon oxidative decarboxylation in the presence of ATP. Provides a bioluminescent signal for cellular ATP levels in vivo. Water soluble analogs are D-Luciferin potassium salt (ab143655) and D-Luciferin sodium salt (ab145164).
  • Purity

    > 98%
  • CAS Number

    2591-17-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2Z,4S)-2-(6-Oxo-1,3-benzothiazol-2-ylidene)-1,3-thiazolidine-4-carboxylic acid

  • Molecular weight

    280.32
  • Molecular formula

    C11H8N2O3S2
  • PubChem identifier

    5459882
  • Storage instructions

    Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
  • Solubility overview

    Soluble in ethanol to 25 mM and in DMSO to 100 mM

  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1C(NC(=C2N=C3C=CC(=O)C=C3S2)S1)C(=O)O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Fet N  et al. In vivo characterisation of the inflammatory reaction following mesh implantation in transgenic mice models. Langenbecks Arch Surg 399:579-88 (2014). Read more (PubMed: 24733521) »
  • Inoue Y  et al. Comparison of subcutaneous and intraperitoneal injection of D-luciferin for in vivo bioluminescence imaging. Eur J Nucl Med Mol Imaging 36:771-9 (2009). Read more (PubMed: 19096841) »
  • Zhang Y  et al. Influence of bioluminescence imaging dynamics by D-luciferin uptake and efflux mechanisms. Mol Imaging 11:499-506 (0). Read more (PubMed: 23084250) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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