D-Luciferin potassium salt, chemiluminescent luciferase substrate (ab143655)

Overview

  • Product name

    D-Luciferin potassium salt, chemiluminescent luciferase substrate
  • Description

    Chemiluminescent luciferase substrate
  • Biological description

    Chemiluminescent luciferase substrate. Water soluble D-Luciferin (ab143654) derivative and D-Luciferin sodium salt (ab145164) analog. Emits light on oxidative decarboxylation in the presence of ATP providing a bioluminescent signal for cellular ATP levels in vivo.
  • Purity

    > 98%
  • CAS Number

    115144-35-9
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    (2Z,4S)-2-(6-Oxo-1,3-benzothiazol-2-ylidene)-1,3-thiazolidine-4-carboxylate potassium salt
  • Molecular weight

    318.42
  • Molecular formula

    C11H7KN2O3S2
  • PubChem identifier

    23703111
  • Storage instructions

    Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.
  • Solubility overview

    Soluble in water to 100 mM and in ethanol to 25 mM. Soluble in PBS (pH between 6.1 and 6.5) to 25 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1C(NC(=C2N=C3C=CC(=O)C=C3S2)S1)C(=O)[O-].[K+]
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Henriques C  et al. In vivo imaging of mice infected with bioluminescent Trypanosoma cruzi unveils novel sites of infection. Parasit Vectors 7:89 (2014). Read more (PubMed: 24589192) »
  • Patrick PS  et al. Oatp1 Enhances Bioluminescence by Acting as a Plasma Membrane Transporter for D-luciferin. Mol Imaging Biol : (2014). Read more (PubMed: 24798747) »
  • Zhang Y  et al. Influence of bioluminescence imaging dynamics by D-luciferin uptake and efflux mechanisms. Mol Imaging 11:499-506 (0). Read more (PubMed: 23084250) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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