Key features and details
- Ghrelin receptor (GHS-R1a) and CCR5 antagonist
- CAS Number: 136054-22-3
- Purity: > 98%
- Soluble in water
- Form / State: Solid
- Source: Synthetic
Product name[D-Lys3]-GHRP-6 (DLS), Ghrelin receptor (GHS-R1a) and CCR5 antagonist
DescriptionGhrelin receptor (GHS-R1a) and CCR5 antagonist
Ghrelin receptor (GHS-R1a) (IC50 = 0.9 μM) antagonist. Additionally acts as CCR5 antagonist and blocks HIV-1 propagation. Active in vivo.
SequenceHWKWFK (Modifications: C-terminal amide; Trp-2 = D-Trp; Lys-3 = D-Lys; Phe-5 = D-Phe)
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab141148 has been referenced in 1 publication.
- Galic S et al. AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis. Elife 7:N/A (2018). PubMed: 29433631