Overview

  • Product name
  • Description
    Rabbit polyclonal to D4 GDI
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human D4 GDI.
    Database link: P52566

  • Positive control
    • Placenta and tonsil.

Properties

Applications

Our Abpromise guarantee covers the use of ab15198 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

1/100 for 10 min at RT. Boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.

WB Use a concentration of 1 µg/ml. Predicted molecular weight: 23 kDa.

Target

  • Function
    Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:8356058, PubMed:7512369). Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133).
  • Tissue specificity
    Detected in bone marrow, thymus and spleen.
  • Sequence similarities
    Belongs to the Rho GDI family.
  • Cellular localization
    Cytoplasm, cytosol.
  • Information by UniProt
  • Database links
  • Alternative names
    • Arhgdib antibody
    • D4 antibody
    • D4 GDP dissociation inhibitor antibody
    • GDIA 2 antibody
    • GDIA2 antibody
    • GDID 4 antibody
    • GDID4 antibody
    • GDIR2_HUMAN antibody
    • GDP dissociation inhibitor D4 antibody
    • LY GDI antibody
    • Ly-GDI antibody
    • LYGDI antibody
    • MGC108926 antibody
    • RAP1GN1 antibody
    • Rho GDI 2 antibody
    • Rho GDI beta antibody
    • Rho GDI2 antibody
    • Rho GDP dissociation inhibitor (GDI) beta antibody
    • Rho GDP dissociation inhibitor 2 antibody
    • Rho GDP dissociation inhibitor beta antibody
    • Rho GDP-dissociation inhibitor 2 antibody
    • Rho-GDI beta antibody
    • RhoGDI2 antibody
    see all

Images

  • ab15198 staining D4 GDI in human tonsil by Immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections).

  • Anti-D4 GDI antibody (ab15198) at 1/25 dilution + Jurkat cell lysate

    Predicted band size: 23 kDa
    Observed band size: 23 kDa

References

This product has been referenced in:
  • Mercey O  et al. Characterizing isomiR variants within the microRNA-34/449 family. FEBS Lett 591:693-705 (2017). WB . Read more (PubMed: 28192603) »
  • Lai MC  et al. Prognostic value of Rho GDP dissociation inhibitors in patients with hepatocellular carcinoma following liver transplantation. Oncol Lett 14:1395-1402 (2017). Read more (PubMed: 28789355) »
See all 6 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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