Overview

  • Product name

  • Description

    Rabbit polyclonal to D4 GDI
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Chicken, Cow, Human, Pig
  • Immunogen

    Recombinant fragment within Human D4 GDI (internal sequence). The exact sequence is proprietary.
    Database link: P52566

  • Positive control

    • WB: HEK-293T, A431, NCI-H1299, HeLa S3 and HepG2 whole cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab227093 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 23 kDa.

Target

  • Function

    Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (PubMed:8356058, PubMed:7512369). Regulates reorganization of the actin cytoskeleton mediated by Rho family members (PubMed:8262133).
  • Tissue specificity

    Detected in bone marrow, thymus and spleen.
  • Sequence similarities

    Belongs to the Rho GDI family.
  • Cellular localization

    Cytoplasm, cytosol.
  • Information by UniProt
  • Database links

  • Alternative names

    • Arhgdib antibody
    • D4 antibody
    • D4 GDP dissociation inhibitor antibody
    • GDIA 2 antibody
    • GDIA2 antibody
    • GDID 4 antibody
    • GDID4 antibody
    • GDIR2_HUMAN antibody
    • GDP dissociation inhibitor D4 antibody
    • LY GDI antibody
    • Ly-GDI antibody
    • LYGDI antibody
    • MGC108926 antibody
    • RAP1GN1 antibody
    • Rho GDI 2 antibody
    • Rho GDI beta antibody
    • Rho GDI2 antibody
    • Rho GDP dissociation inhibitor (GDI) beta antibody
    • Rho GDP dissociation inhibitor 2 antibody
    • Rho GDP dissociation inhibitor beta antibody
    • Rho GDP-dissociation inhibitor 2 antibody
    • Rho-GDI beta antibody
    • RhoGDI2 antibody
    see all

Images

  • All lanes : Anti-D4 GDI antibody (ab227093) at 1/1000 dilution

    Lane 1 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate
    Lane 2 : A431 (human epidermoid carcinoma cell line) whole cell lysate
    Lane 3 : NCI-H1299 (human lung carcinoma cell line) whole cell lysate
    Lane 4 : HeLa S3 (human epithelial cell line from cervix adenocarcinoma) whole cell lysate
    Lane 5 : HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Secondary
    All lanes : HRP-conjugated anti-rabbit IgG

    Predicted band size: 23 kDa



    12% SDS-PAGE gel.

References

ab227093 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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