Key features and details
- Rabbit polyclonal to Dab1
- Suitable for: IHC-P, ICC/IF, WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Dab1 antibody
See all Dab1 primary antibodies
DescriptionRabbit polyclonal to Dab1
Tested applicationsSuitable for: IHC-P, ICC/IF, WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
- Human intestine tissue; MCF7 cells; extracts from HepG2 and 293 cells.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, 49% PBS
PBS is without Mg
/sup> and Ca2+ /sup>.
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab189426 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 20 µg/ml.|
|ICC/IF||1/100 - 1/500.|
|WB||1/500 - 1/1000. Predicted molecular weight: 60 kDa.|
FunctionAdapter molecule functioning in neural development. May regulate SIAH1 activity.
Sequence similaritiesContains 1 PID domain.
DomainThe PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.
modificationsPhosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.
- Information by UniProt
- Dab 1 antibody
- Dab reelin signal transducer 1 antibody
- Dab, reelin signal transducer, homolog 1 (Drosophila) antibody
All lanes : Anti-Dab1 antibody (ab189426) at 1/500 dilution
Lane 1 : Extracts from HepG2 cells
Lane 2 : Extracts from 293 cells
Lane 3 : Extracts from HepG2 cells treated with the synthesized peptide
Predicted band size: 60 kDa
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human intestine tissue labeling Dab1 with ab189426 at 20 µg/ml.
Immunofluorescent analysis of MCF7 cells labeling Dab1 with ab189426 at 1/100 dilution. The image on the right is treated with the synthesized peptide.
ab189426 has not yet been referenced specifically in any publications.