Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EP2248Y] to Dab1
- Suitable for: WB
- Reacts with: Rat
Related conjugates and formulations
Product nameAnti-Dab1 antibody [EP2248Y]
See all Dab1 primary antibodies
DescriptionRabbit monoclonal [EP2248Y] to Dab1
Tested applicationsSuitable for: WBmore details
Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
Species reactivityReacts with: Rat
Predicted to work with: Mouse
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
- Rat brain lysate.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Human: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant
Concentration information loading...
PurityProtein A purified
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab68461 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Is unsuitable for Flow Cyt, ICC/IF, IHC-P or IP.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionAdapter molecule functioning in neural development. May regulate SIAH1 activity.
Sequence similaritiesContains 1 PID domain.
DomainThe PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.
modificationsPhosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.
- Information by UniProt
- Dab 1 antibody
- Dab reelin signal transducer 1 antibody
- Dab, reelin signal transducer, homolog 1 (Drosophila) antibody
Anti-Dab1 antibody [EP2248Y] (ab68461) at 1/2000 dilution + Rat brain lysate at 10 µg
HRP conjugated Goat anti Rabbit. at 1/2000 dilution
Predicted band size: 67 kDa
Observed band size: 70 kDa why is the actual band size different from the predicted?
ab68461 has not yet been referenced specifically in any publications.