Key features and details
- Rabbit polyclonal to Dab1 (phospho Y232)
- Suitable for: WB, ELISA
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Dab1 (phospho Y232) antibody
See all Dab1 primary antibodies
DescriptionRabbit polyclonal to Dab1 (phospho Y232)
SpecificityThis antibody detects endogenous levels of Dab1 only when phosphorylated at tyrosine 232.
Tested applicationsSuitable for: WB, ELISAmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthesized phosphopeptide derived from human Dab1 around the phosphorylation site of tyrosine 232 (G-V-YP-D-V).
- Extracts from LOVO cells.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
Concentration information loading...
PurityImmunogen affinity purified
Purification notesThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Our Abpromise guarantee covers the use of ab78200 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Detects a band of approximately 67 kDa (predicted molecular weight: 67 kDa).|
FunctionAdapter molecule functioning in neural development. May regulate SIAH1 activity.
Sequence similaritiesContains 1 PID domain.
DomainThe PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in many tyrosine-phosphorylated proteins.
modificationsPhosphorylated on Tyr-198 and Tyr-220 upon reelin induction in embryonic neurons (By similarity). Also phosphorylated on Ser-524 independently of reelin signaling.
- Information by UniProt
- Dab 1 antibody
- Dab reelin signal transducer 1 antibody
- Dab, reelin signal transducer, homolog 1 (Drosophila) antibody
ab78200 has been referenced in 1 publication.
- Rogers JT et al. Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density. Learn Mem 18:558-64 (2011). PubMed: 21852430