Overview

  • Product name

    Anti-DAB2 antibody [EPR2249]
    See all DAB2 primary antibodies
  • Description

    Rabbit monoclonal [EPR2249] to DAB2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IP, Flow Cytmore details
    Unsuitable for: ICC or IHC-P
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human DAB2. The exact sequence is proprietary.

  • Positive control

    • HeLa cell lysate
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab133356 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 82 kDa.
IP 1/10.
Flow Cyt 1/50.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

 

  • Application notes
    Is unsuitable for ICC or IHC-P.
  • Target

    • Relevance

      DAB2 is a component of the CSF1 signal transduction pathway. DAB2 mRNA is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines. The down regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2 like domains, alpha and beta).
    • Cellular localization

      Cytoplasmic vesicle; clathrin coated vesicle; clathrin coated vesicle membrane. Cell membrane; coated pit; clathrin coated pit. Note: Colocalizes with large insert containing isoforms of MYO6 at clathrin coated pits/vesicles.
    • Database links

    • Alternative names

      • DAB 2 antibody
      • Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) antibody
      • DAB2 antibody
      • Differentially expressed in ovarian cancer 2 antibody
      • Differentially expressed protein 2 antibody
      • Disabled (Drosophila) homolog 2 (mitogen responsive phosphoprotein) antibody
      • Disabled homolog 2 antibody
      • Disabled homolog 2 mitogen responsive phosphoprotein (Drosophila) antibody
      • Disabled homolog 2 mitogen responsive phosphoprotein antibody
      • Disabled, Drosophila, homolog of, 2 antibody
      • DOC 2 antibody
      • DOC2 antibody
      • FLJ26626 antibody
      • Mitogen responsive phosphoprotein antibody
      see all

    Images

    • Anti-DAB2 antibody [EPR2249] (ab133356) at 1/1000 dilution + HeLa cell lysate at 10 µg

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 82 kDa

    References

    ab133356 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab133356.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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