Overview

  • Product name

    Dacarbazine, DNA alkylating agent
  • Description

    DNA alkylating agent. Chemotherapeutic.
  • Biological description

    DNA alkylating agent. Chemotherapeutic. Induces cell cycle arrest and cell death in vitro and in vivo. Crosses the blood-brain barrier.
  • Purity

    > 99%
  • CAS Number

    4342-03-4
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Thallinger C  et al. Orally administered rapamycin, dacarbazine or both for treatment of human melanoma evaluated in severe combined immunodeficiency mice. Pharmacology 82:233-8 (2008). Read more (PubMed: 18810248) »
  • Lev DC  et al. Exposure of melanoma cells to dacarbazine results in enhanced tumor growth and metastasis in vivo. J Clin Oncol 22:2092-100 (2004). Read more (PubMed: 15123733) »
  • van den Bent MJ The role of chemotherapy in brain metastases. Eur J Cancer 39:2114-20 (2003). Read more (PubMed: 14522368) »

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