Dansyl chloride, Fluorogenic primary amine reactive reagent (ab146397)

Overview

  • Product name

    Dansyl chloride, Fluorogenic primary amine reactive reagent
  • Description

    Fluorogenic primary amine reactive reagent.
  • Alternative names

    • 5-(Dimethylamino)-1-naphthalenesulfonyl chloride
    • 5-(Dimethylamino)naphthalene-1-sulfonyl chloride
    • DNS chloride
    • DNSCl
    • l-dimethylaminonaphthalene-5-sulfonyl chloride
    see all
  • Biological description

    Fluorogenic primary amine reactive reagent for N-terminal derivatization of amino acids and peptides, and for polyamine detection by reverse phase HPLC and other analytical procedures.


    Fluorescence: λex 337 nm; λem 492 nm in chloroform (after derivatization with hexylamine).

  • Purity

    > 95%
  • CAS Number

    605-65-2
  • Chemical structure

    Chemical Structure

Properties

  • Excitation

    337nm
  • Emission

    492nm
  • Chemical name

    5-(Dimethylamino)-1-naphthalenesulfonyl chloride
  • Molecular weight

    269.75
  • Molecular formula

    C12H12ClNO2S
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Zhuang X  et al. Pre-column derivatization combined with UHPLC-MS/MS for rapid and sensitive quantification of bakuchiol in rat plasma. J Pharm Biomed Anal 75:18-24 (2013). Read more (PubMed: 23312380) »
  • Aydogmus Z  et al. Spectrofluorimetric determination of aliskiren in tablets and spiked human plasma through derivatization with dansyl chloride. J Fluoresc 22:549-56 (2012). Read more (PubMed: 21953437) »
  • Jia S  et al. Simultaneous determination of 23 amino acids and 7 biogenic amines in fermented food samples by liquid chromatography/quadrupole time-of-flight mass spectrometry. J Chromatogr A 1218:9174-82 (2011). Read more (PubMed: 22074649) »
  • Walker JM The dansyl method for identifying N-terminal amino acids. Methods Mol Biol 1:203-12 (1984). Read more (PubMed: 20512690) »

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