Product nameDansyl chloride, Fluorogenic primary amine reactive reagent
DescriptionFluorogenic primary amine reactive reagent.
- 5-(Dimethylamino)-1-naphthalenesulfonyl chloride
- 5-(Dimethylamino)naphthalene-1-sulfonyl chloride
- DNS chloride
Fluorogenic primary amine reactive reagent for N-terminal derivatization of amino acids and peptides, and for polyamine detection by reverse phase HPLC and other analytical procedures.
Fluorescence: λex 337 nm; λem 492 nm in chloroform (after derivatization with hexylamine).
Chemical name5-(Dimethylamino)-1-naphthalenesulfonyl chloride
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This product has been referenced in:
- Zhuang X et al. Pre-column derivatization combined with UHPLC-MS/MS for rapid and sensitive quantification of bakuchiol in rat plasma. J Pharm Biomed Anal 75:18-24 (2013). Read more (PubMed: 23312380) »
- Aydogmus Z et al. Spectrofluorimetric determination of aliskiren in tablets and spiked human plasma through derivatization with dansyl chloride. J Fluoresc 22:549-56 (2012). Read more (PubMed: 21953437) »
- Jia S et al. Simultaneous determination of 23 amino acids and 7 biogenic amines in fermented food samples by liquid chromatography/quadrupole time-of-flight mass spectrometry. J Chromatogr A 1218:9174-82 (2011). Read more (PubMed: 22074649) »
- Walker JM The dansyl method for identifying N-terminal amino acids. Methods Mol Biol 1:203-12 (1984). Read more (PubMed: 20512690) »