Overview

  • Product name

    Anti-DAP Kinase 1 antibody
    See all DAP Kinase 1 primary antibodies
  • Description

    Rabbit polyclonal to DAP Kinase 1
  • Host species

    Rabbit
  • Specificity

    This antibody detects endogenous levels of total DAP Kinase 1 protein.
  • Tested applications

    Suitable for: ICC/IF, IHC-Pmore details
  • Species reactivity

    Reacts with: Human, African green monkey
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide within Human DAP Kinase 1 aa 274-323. The exact sequence is proprietary.
    Sequence:

    WIKPKDT QQALSRKASA VNMEKFKKFA ARKKWKQSVR LISLCQRLSR SFL


    Database link: P53355

  • Positive control

    • Human spleen tissue and COS7 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab197783 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF 1/100 - 1/500.
IHC-P Use a concentration of 5 µg/ml.

Target

  • Function

    Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis.
  • Sequence similarities

    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
    Contains 10 ANK repeats.
    Contains 1 death domain.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications

    Ubiquitinated by the BCR(KLHL20) E3 ubiquitin ligase complex, leading to its degradation by the proteasome.
  • Cellular localization

    Cytoplasm. Colocalizes with the actin filament system.
  • Information by UniProt
  • Database links

  • Alternative names

    • DAK1 antibody
    • DAP K1 antibody
    • DAP kinase 1 antibody
    • DAPK 1 antibody
    • DAPK antibody
    • DAPK1 antibody
    • DAPK1_HUMAN antibody
    • Death Associated Protein Kinase 1 antibody
    • Death-associated protein kinase 1 antibody
    • DKFZp781I035 antibody
    see all

Images

  • Immunofluorescence of COS7 cells, labeling DAP Kinase 1 using ab197783 at a 1/100 dilution. The sample on the right was
    incubated with synthetic peptide.

References

ab197783 has not yet been referenced specifically in any publications.

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