Overview

  • Product name

    Anti-DAP Kinase 1 antibody
    See all DAP Kinase 1 primary antibodies
  • Description

    Rabbit polyclonal to DAP Kinase 1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Dog, Rhesus monkey
  • Immunogen

    Recombinant fragment within Human DAP Kinase 1 aa 38-374. The exact sequence is proprietary. NP_004929.2.
    Database link: P53355

  • Positive control

    • Human Placenta tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab200549 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 160 kDa.
IHC-P Use a concentration of 5 - 10 µg/ml.

Target

  • Function

    Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis.
  • Sequence similarities

    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. DAP kinase subfamily.
    Contains 10 ANK repeats.
    Contains 1 death domain.
    Contains 1 protein kinase domain.
  • Post-translational
    modifications

    Ubiquitinated by the BCR(KLHL20) E3 ubiquitin ligase complex, leading to its degradation by the proteasome.
  • Cellular localization

    Cytoplasm. Colocalizes with the actin filament system.
  • Information by UniProt
  • Database links

  • Alternative names

    • DAK1 antibody
    • DAP K1 antibody
    • DAP kinase 1 antibody
    • DAPK 1 antibody
    • DAPK antibody
    • DAPK1 antibody
    • DAPK1_HUMAN antibody
    • Death Associated Protein Kinase 1 antibody
    • Death-associated protein kinase 1 antibody
    • DKFZp781I035 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human placenta tissue labeling DAP Kinase 1 with ab200549 at 10 μg/ml.

References

This product has been referenced in:

  • Prokesch A  et al. Placental DAPK1 and autophagy marker LC3B-II are dysregulated by TNF-a in a gestational age-dependent manner. Histochem Cell Biol 147:695-705 (2017). Read more (PubMed: 28097431) »
See 1 Publication for this product

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