Key features and details
- Potent, selective CCR5 antagonist
- CAS Number: 106362-34-9
- Purity: > 95%
- Soluble in water to 1 mg/ml
- Form / State: Solid
- Source: Synthetic
Product nameDAPTA, CCR5 antagonist
DescriptionPotent, selective CCR5 antagonist
Potent, selective CCR5 antagonist. Synthetic peptide. Selective antiviral entry inhibitor for R5 tropic HIV-1 isolates. Able to attenuate neuroinflammation.
SequenceASTTTNYT (Modifications: C-terminal amide; Ala-1 = D-Ala)
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 1 mg/ml
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120810 has been referenced in 1 publication.
- Yu W et al. miR-4456/CCL3/CCR5 Pathway in the Pathogenesis of Tight Junction Impairment in Chronic Obstructive Pulmonary Disease. Front Pharmacol 12:551839 (2021). PubMed: 33953665