Dasatinib, Src family tyrosine kinase (SFK)/Bcl-Abl kinase inhibitor (ab142050)
Key features and details
- Potent Src family tyrosine kinase (SFK)/Bcl-Abl kinase inhibitor
- CAS Number: 302962-49-8
- Purity: > 98%
- Soluble in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Dasatinib, Src family tyrosine kinase (SFK)/Bcl-Abl kinase inhibitor -
Description
Potent Src family tyrosine kinase (SFK)/Bcl-Abl kinase inhibitor -
Alternative names
- BMS 354825
- BMS354825
- Sprycel
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Biological description
Potent Src family tyrosine kinase (SFK)/Bcl-Abl kinase inhibitor. Inhibits growth of Bcr-Abl–dependent chronic myeloid leukemia xenografts in nude mice. Anti-tumor activity in vivo.
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Purity
> 98% -
CAS Number
302962-49-8 -
Chemical structure
Properties
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Chemical name
N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide -
Molecular weight
488.01 -
Molecular formula
C22H26ClN7O2S -
PubChem identifier
3062316 -
Storage instructions
Shipped at Room Temperature. Store at -20°C. Store under desiccating conditions. -
Solubility overview
Soluble in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=NC(=NC(=C3)N4CCN(CC4)CCO)C -
Source
Synthetic
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Research areas
Associated products
Images
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Chemical Structure - Dasatinib, Src family tyrosine kinase (SFK)/Bcl-Abl kinase inhibitor (ab142050)2D chemical structure image of ab142050, Dasatinib, Src family tyrosine kinase (SFK)/Bcl-Abl kinase inhibitor
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab142050 has not yet been referenced specifically in any publications.