Daunorubicin hydrochloride, Anthracycline antibiotic (ab141394)
Key features and details
- Anthracycline antibiotic. DNA and RNA synthesis inhibitor.
- CAS Number: 23541-50-6
- Purity: > 95%
- Soluble in water to 50 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Daunorubicin hydrochloride, Anthracycline antibiotic -
Description
Anthracycline antibiotic. DNA and RNA synthesis inhibitor. -
Biological description
Anthracycline antibiotic. DNA and RNA synthesis inhibitor. Reduces tau mRNA levels. Induces DNA fragmentation and apoptosis. Antiproliferative and cytotoxic effects in vivo. Orally active. -
Purity
> 95% -
CAS Number
23541-50-6 -
Chemical structure
Properties
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Chemical name
(7S,9S)-9-Acetyl-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione hydrochloride -
Molecular weight
563.98 -
Molecular formula
C27H29NO10.HCl -
PubChem identifier
62770 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 50 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)C)O)N)O.Cl -
Source
Synthetic
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Research areas
- Signal Transduction
- Signaling Pathway
- Nuclear Signaling
- Nuclear Hormone Receptors
- Retinoic & Retinoid
- Epigenetics and Nuclear Signaling
- Nuclear Signaling Pathways
- Nuclear Receptors
- Orphan Nuclear Receptors
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Nucleotide metabolism
- Molecular processes
- Mitochondrial transcription
- Metabolism
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Lipid metabolism
Images
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Chemical Structure - Daunorubicin hydrochloride, Anthracycline antibiotic (ab141394)2D chemical structure image of ab141394, Daunorubicin hydrochloride, Anthracycline antibiotic
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab141394 has not yet been referenced specifically in any publications.