Overview

  • Product name

    Daunorubicin hydrochloride, Anthracycline antibiotic
  • Description

    Anthracycline antibiotic. DNA and RNA synthesis inhibitor.
  • Biological description

    Anthracycline antibiotic. DNA and RNA synthesis inhibitor. Reduces tau mRNA levels. Induces DNA fragmentation and apoptosis. Antiproliferative and cytotoxic effects in vivo. Orally active.
  • Purity

    > 95%
  • CAS Number

    23541-50-6
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Liu J  et al. A modified double-emulsion method for the preparation of daunorubicin-loaded polymeric nanoparticle with enhanced in vitro anti-tumor activity. Biomed Mater 5:065002 (2010). Read more (PubMed: 20924138) »
  • Gewirtz DA A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem Pharmacol 57:727-41 (1999). Read more (PubMed: 10075079) »
  • Boland MP  et al. Daunorubicin activates NFkappaB and induces kappaB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cells. J Biol Chem 272:12952-60 (1997). Read more (PubMed: 9148901) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab141394.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up