Key features and details
- Rabbit polyclonal to DAZ2
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-DAZ2 antibody
See all DAZ2 primary antibodies
DescriptionRabbit polyclonal to DAZ2
Tested applicationsSuitable for: WB, ICC/IFmore details
Species reactivityReacts with: Human
Recombinant protein fragment corresponding to a region within amino acids 1 - 207 of Human DAZ2 (NP_065096).
- WB: 293T, A431, HeLa, MOLT4 and Raji cell lysate IF: HeLa cells
Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab97772 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 63 kDa.|
|ICC/IF||1/100 - 1/200.|
FunctionRNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.
Tissue specificityTestis specific.
Involvement in diseaseDefects in DAZ2 may be a cause of spermatogenic failure Y-linked type 2 (SPGFY2) [MIM:415000]. It is a disorder resulting in the absence (azoospermia) or reduction (oligozoospermia) of sperm in the semen, leading to male infertility. Note=AZFc deletions in the Yq11.23 region including the DAZ genes are the most common known genetic cause of human male infertility.
Sequence similaritiesBelongs to the RRM DAZ family.
Contains 15 DAZ-like domains.
Contains 1 RRM (RNA recognition motif) domain.
DomainThe DAZ-like repeats are essential and mediate the interaction with DAZAP1 and DAZAP2.
Cellular localizationCytoplasm. Nucleus. Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.
- Information by UniProt
- DAZ2 antibody
- DAZ2_HUMAN antibody
- DAZ3 antibody
ab97772 has not yet been referenced specifically in any publications.