Overview

  • Product name

  • Description

    Rabbit polyclonal to DAZL
  • Host species

    Rabbit
  • Specificity

    Reacts with Xenopus DAZL protein: dazl-a and dazl-b.
  • Tested applications

    Suitable for: WB, ELISAmore details
  • Species reactivity

    Reacts with: Xenopus laevis
    Predicted to work with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide derived from the internal domain of Human DAZL.

Properties

Applications

Our Abpromise guarantee covers the use of ab128238 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 33 kDa.
ELISA Use at an assay dependent concentration.

Target

  • Function

    RNA-binding protein, which is essential for gametogenesis. Plays a central role during spermatogenesis. May act by binding to the 3'-UTR of mRNA and thereby regulating the translation of key transcripts.
  • Tissue specificity

    Testis specific.
  • Sequence similarities

    Belongs to the RRM DAZ family.
    Contains 1 DAZ-like domain.
    Contains 1 RRM (RNA recognition motif) domain.
  • Domain

    The DAZ-like domain mediates the interaction with DAZAP1 and DAZAP2.
  • Cellular localization

    Cytoplasm. Nucleus. Predominantly cytoplasmic (By similarity). Nuclear in spermatogonia until near the end of the meiotic prophase and cytoplasmic localization from then onward.
  • Information by UniProt
  • Database links

  • Alternative names

    • DAZ homolog antibody
    • DAZ like autosomal antibody
    • DAZ-like autosomal antibody
    • DAZH antibody
    • DAZL 1 antibody
    • DAZL antibody
    • DAZL_HUMAN antibody
    • DAZL1 antibody
    • DAZLA antibody
    • Deleted in azoospermia like 1 antibody
    • Deleted in azoospermia like antibody
    • Deleted in azoospermia like autosomal antibody
    • Deleted in azoospermia-like 1 antibody
    • Deleted in azoospermia-like antibody
    • Germline specific RNA binding protein antibody
    • MGC26406 antibody
    • Spermatogenesis gene on the Y like autosomal antibody
    • SPGY like autosomal antibody
    • SPGY-like-autosomal antibody
    • SPGYLA antibody
    • Tpx2 antibody
    see all

References

This product has been referenced in:

  • Ding X  et al. Human GV oocytes generated by mitotically active germ cells obtained from follicular aspirates. Sci Rep 6:28218 (2016). Read more (PubMed: 27357640) »
See 1 Publication for this product

Customer reviews and Q&As

Application
Immunocytochemistry/ Immunofluorescence
Sample
Xenopus laevis Cell (Testis)
Permeabilization
Yes - Tween-20
Specification
Testis
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 22°C
Fixative
Paraformaldehyde

Abcam user community

Verified customer

Submitted Jul 17 2017

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