Overview

  • Product name

    Anti-DBC1 antibody [EPR7311]
    See all DBC1 primary antibodies
  • Description

    Rabbit monoclonal [EPR7311] to DBC1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, Flow Cytmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human DBC1 aa 1-100. The exact sequence is proprietary.

  • Positive control

    • Human fetal heart and MCF7 cell lysates; MCF7 cells.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab128890 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000 - 1/50000. Detects a band of approximately 88 kDa (predicted molecular weight: 89 kDa).
Flow Cyt 1/10 - 1/100.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

 

  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Function

      Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway.
    • Tissue specificity

      Highly expressed in brain. Weakly expressed in heart, lung, skeletal muscle, kidney, thymus, prostate, testis and small intestine.
    • Sequence similarities

      Belongs to the FAM5 family.
      Contains 1 MACPF domain.
    • Cellular localization

      Cytoplasm.
    • Information by UniProt
    • Database links

    • Alternative names

      • BMP/retinoic acid-inducible neural-specific protein 1 antibody
      • BRINP1 antibody
      • DBC1 antibody
      • DBC1_HUMAN antibody
      • DBCCR1 antibody
      • Deleted in bladder cancer protein 1 antibody
      • Deleted in bladder cancer protein 1 precursor antibody
      • FAM5A antibody
      • IB3089A antibody
      • Protein FAM5A antibody
      see all

    Images

    • All lanes : Anti-DBC1 antibody [EPR7311] (ab128890) at 1/10000 dilution

      Lane 1 : Human fetal heart lysate
      Lane 2 : MCF7 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit IgG at 1/2000 dilution

      Predicted band size: 89 kDa

    • ab128890 at 1/10 dilution staining DBC1 in permeabilized MCF7 cells by Flow cytometry (red). Rabbit IgG negative control (green).
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    This product has been referenced in:

    • Li L  et al. NANOGP8 expression regulates gastric cancer cell progression by transactivating DBC1 in gastric cancer MKN-45 cells. Oncol Lett 17:555-563 (2019). Read more (PubMed: 30655801) »
    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab128890.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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