Overview

  • Product name

    Anti-DBC1 antibody - N-terminal
    See all DBC1 primary antibodies
  • Description

    Rabbit polyclonal to DBC1 - N-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, ICC/IF, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
    Predicted to work with: Rhesus monkey
  • Immunogen

    Recombinant fragment within Human DBC1 aa 1-205 (N terminal). The exact sequence is proprietary.
    Sequence:

    MNWRFVELLY FLFIWGRISV QPSHQEPAGT DQHVSKEFDW LISDRGPFHH SRSYLSFVER HRQGFTTRYK IYREFARWKV RNTAIERRDL VRHPVPLMPE FQRSIRLLGR RPTTQQFIDT IIKKYGTHLL ISATLGGEEA LTMYMDKSRL DRKSGNATQS VEALHQLASS YFVDRDGTMR RLHEIQISTG AIKVTETRTG PLGCN


    Database link: O60477

  • Positive control

    • MCF7 whole cell lysate; MCF7 cells; mouse kidney and rat hind brain tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab183850 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 89 kDa.
ICC/IF 1/100 - 1/1000.
IHC-P 1/100 - 1/1000.

Target

  • Function

    Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway.
  • Tissue specificity

    Highly expressed in brain. Weakly expressed in heart, lung, skeletal muscle, kidney, thymus, prostate, testis and small intestine.
  • Sequence similarities

    Belongs to the FAM5 family.
    Contains 1 MACPF domain.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • BMP/retinoic acid-inducible neural-specific protein 1 antibody
    • BRINP1 antibody
    • DBC1 antibody
    • DBC1_HUMAN antibody
    • DBCCR1 antibody
    • Deleted in bladder cancer protein 1 antibody
    • Deleted in bladder cancer protein 1 precursor antibody
    • FAM5A antibody
    • IB3089A antibody
    • Protein FAM5A antibody
    see all

Images

  • Anti-DBC1 antibody - N-terminal (ab183850) at 1/500 dilution + MCF7 whole cell lysate at 30 µg

    Predicted band size: 89 kDa

  • Immunohistochemical analysis of paraffin embedded rat hind brain tissue labeling DBC1 with ab183850 at 1/500.

  • Immunohistochemical analysis of paraffin embedded mouse kidney tissue labeling DBC1 with ab183850 at 1/500.

  • Immunofluorescent analysis of MCF7 cells labeling DBC1 with ab183850 at 1/500. Image at the right stained with Hoechst 33342. Note: cells were fixed in 100% MeOH for 5 min.

References

ab183850 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab183850.
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