Key features and details
- Rabbit polyclonal to DBX1
- Suitable for: WB, ICC/IF, IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-DBX1 antibody
See all DBX1 primary antibodies
DescriptionRabbit polyclonal to DBX1
Specificityab156283 is predicted to not cross-react with other DBX protein family members.
Tested applicationsSuitable for: WB, ICC/IF, IHC-Pmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide, corresponding to 15 internal sequence amino acids of Human DBX1 (NP_001025036).
- Mouse kidney tissue lysate; Human kidney tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferPreservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab156283 is affinity chromatography purified via peptide column.
Our Abpromise guarantee covers the use of ab156283 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 37 kDa.|
|ICC/IF||Use a concentration of 20 µg/ml.|
|IHC-P||Use a concentration of 2.5 µg/ml.|
RelevanceDbx1 homeodomain transcription factor is expressed in progenitors at the boundary between the dorsal and ventral plates of the caudal neural tube, from which postmitotic cells migrate tangentially to their final destination. Dbx1 is implicated in patterning the central nervous system during embryogenesis. Cell fate allocation and cell diversity are determined at very early stages in progenitor cells at precise coordinates along the dorsoventral and anteroposterior axis. In the spinal cord, the spatially restricted expression of Dbx1 in progenitors is critical in establishing interneuron cell fates and helps coordinate diverse phenotypic features. In the telencephalon, Dbx1 is expressed in restricted progenitor domains at the borders of the developing pallium.
- dbx antibody
- Developing brain homeobox 1 antibody
- Developing brain homeobox protein 1 antibody
- Homeobox protein DBX1 antibody
Immunofluorescence of DBX1 in Human kidney tissue with ab156283 at 20 ug/mL.
Lane 1 : Anti-DBX1 antibody (ab156283) at 1 µg/ml
Lane 2 : Anti-DBX1 antibody (ab156283) at 2 µg/ml
All lanes : Mouse kidney tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 37 kDa
Immunohistochemical analysis of Paraffin-embedded Human kidney tissue labeling DBX1 with ab156283 at 2.5 µg/ml.
ab156283 has been referenced in 1 publication.
- Papadimitriou C et al. 3D Culture Method for Alzheimer's Disease Modeling Reveals Interleukin-4 Rescues Aß42-Induced Loss of Human Neural Stem Cell Plasticity. Dev Cell 46:85-101.e8 (2018). PubMed: 29974866