Overview

  • Product name

  • Description

    Rabbit polyclonal to DCAMKL1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
    Predicted to work with: Chicken
  • Positive control

    • WB: Mouse brain and hippocampus tissue extract. Rat brain tissue extract. U-87 MG, SK-N-SH, IMR32 and SK-N-AS whole cell extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab226967 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 82 kDa.

Target

  • Function

    Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system.
  • Tissue specificity

    In fetal tissues, highly expressed in brain, detectable in lung and liver, but not in kidney. In adult tissues, expressed ubiquitously in the brain, detectable in the heart, liver, spleen, thymus, prostate, testis, ovary, small intestine and colon. The type A isoforms seem to be expressed predominantly in fetal brain whereas type B isoforms are expressed abundantly in both fetal and adult brain.
  • Sequence similarities

    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
    Contains 2 doublecortin domains.
    Contains 1 protein kinase domain.
  • Information by UniProt
  • Database links

  • Alternative names

    • Calcium/calmodulin-dependent protein kinase type I-like CPG16 antibody
    • CL1 antibody
    • CLICK1 antibody
    • Cpg16 antibody
    • DCDC3A antibody
    • Dcl antibody
    • Dclk antibody
    • Dclk1 antibody
    • DCLK1_HUMAN antibody
    • Doublecortin domain-containing protein 3A antibody
    • Doublecortin-like and CAM kinase-like 1 antibody
    • Doublecortin-like kinase 1 antibody
    • KIAA0369 antibody
    • Serine/threonine-protein kinase DCAMKL1 antibody
    • Serine/threonine-protein kinase DCLK1 antibody
    see all

Images

  • All lanes : Anti-DCAMKL1 antibody (ab226967) at 1/1000 dilution

    Lane 1 : U-87 MG (human glioblastoma-astrocytoma epithelial cell line) whole cell extracts
    Lane 2 : SK-N-SH (human neuroblastoma cell line) whole cell extracts
    Lane 3 : IMR32 (human brain neuroblast cell line) whole cell extracts
    Lane 4 : SK-N-AS (human brain neuroblastoma cell line) whole cell extracts

    Developed using the ECL technique.

    Predicted band size: 82 kDa



    7.5% SDS-PAGE

  • All lanes : Anti-DCAMKL1 antibody (ab226967) at 1/5000 dilution

    Lane 1 : Mouse brain tissue extract
    Lane 2 : Rat brain tissue extract

    Lysates/proteins at 50 µg per lane.

    Secondary
    All lanes : HRP-conjugated anti-rabbit IgG antibody

    Developed using the ECL technique.

    Predicted band size: 82 kDa



    7.5% SDS-PAGE

  • Anti-DCAMKL1 antibody (ab226967) at 1/5000 dilution + Mouse hippocampus tissue extract at 50 µg

    Secondary
    HRP-conjugated anti-rabbit IgG

    Developed using the ECL technique.

    Predicted band size: 82 kDa



    7.5% SDS-PAGE

References

ab226967 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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