Overview

  • Product name
  • Description
    Rabbit polyclonal to DCD
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WB, IHC-Fr, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic peptide corresponding to Human DCD aa 96-110.
    Sequence:

    KGAVHDVKDVLDSVL

  • General notes

    Protein previously labeled as Dermcidin.

Properties

Applications

Our Abpromise guarantee covers the use of ab52138 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000. Predicted molecular weight: 11 kDa.
IHC-Fr Use at an assay dependent concentration. See Abreview.
ELISA 1/60000.

Target

  • Function
    DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat.
    Survival-promoting peptide promotes survival of neurons and displays phosphatase activity. It may bind IgG.
  • Tissue specificity
    Specifically and constitutively expressed in eccrine sweat gland cells. Secreted into the sweat at a concentration of 1-10 micrograms/ml.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • AIDD antibody
    • DCD 1 antibody
    • dcd antibody
    • DCD-1 antibody
    • DCD_HUMAN antibody
    • Dermcidin antibody
    • DSEP antibody
    • HCAP antibody
    • PIF antibody
    • Preproteolysin antibody
    see all

Images

  • ab52138 (1/300) detecting DCD in frozen skeletal muscle tissue sections (mouse). Tissues were fixed with paraformaldehyde and blocked in 5% BSA. For further experimental details please refer to abreview.

    See Abreview

References

This product has been referenced in:
  • Wang F  et al. The Warburg effect in human pancreatic cancer cells triggers cachexia in athymic mice carrying the cancer cells. BMC Cancer 18:360 (2018). Read more (PubMed: 29609556) »
See 1 Publication for this product

Customer reviews and Q&As

1-4 of 4 Abreviews or Q&A

Answer

Les 2 anticorps ab52138 et ab83664 sont actuellement en stock et livrables sous 2 jours maximum. Ces informations sont disponibles en consultant les fiches techniques des produits, assurez-vous de bien sélectionner le pays (option en haut à droite des pages du site www.abcam.com).
Pour passer rapidement et directement commande chez Abcam, le plus simple est de contacter notre service clientèle par email à orders@abcam.com ou par téléphone au 061 500 05 30.
J'espère que ces informations vous seront utiles. N'hésitez pas à me contacter de nouveau si vous avez d'autres questions.

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Answer

Merci de nous avoir contactés. J'aimerais vous informer que le peptide immunogène de l'anti-dermcidin ab52138 a été ajouté à notre catalogue sous la référence ab123258. Le lien vers la fiche technique est : www.abcam.com/ab123258. J'espère que ces informations vous seront utiles. N'hésitez pas à nous contacter de nouveau si vous avez d'autres questions.

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Answer

I would recommend contacting the owner of the Abreview directly by clicking on her name above the Abreview.

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Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Immunohistochemistry (Frozen sections)
Sample
Mouse Tissue sections (skeletal muscle)
Specification
skeletal muscle
Fixative
Paraformaldehyde
Permeabilization
No
Blocking step
BSA as blocking agent for 10 minute(s) · Concentration: 5% · Temperature: 37°C

Miss. Silke Vorwald

Verified customer

Submitted Jan 06 2009

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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