Anti-DCDC2/RU2 antibody (ab126539)
Key features and details
- Rabbit polyclonal to DCDC2/RU2
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-DCDC2/RU2 antibody -
Description
Rabbit polyclonal to DCDC2/RU2 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse
Predicted to work with: Rat, Rabbit, Horse, Human, Pig, Chimpanzee, Macaque monkey, Gorilla, Orangutan -
Immunogen
Synthetic peptide corresponding to Mouse DCDC2/RU2 aa 200-300 conjugated to keyhole limpet haemocyanin.
Database link: Q5DU00 -
Positive control
- This antibody gave a positive signal in the following Mouse tissue lysates: Brain (1 day old); Cortex (3 month old); Skeletal Muscle (post natal, 0 day old); Skeletal Muscle (Embryonic, day 18); Placenta.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help. -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab126539 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 52 kDa.
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Notes |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 52 kDa. |
Target
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Function
May be involved in neuronal migration during development of the cerebral neocortex. -
Tissue specificity
Ubiquitously expressed. In brain, highly expressed in the entorhinal cortex, inferior temporal cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus. -
Involvement in disease
Defects in DCDC2 may be a cause of susceptibility to dyslexia type 2 (DYX2) [MIM:600202]; also known as specific reading disability type 2. Dyslexia is a relatively common, complex cognitive disorder that affects 5% to 10% of school-aged children. The disorder is characterized by an impairment of reading performance despite adequate motivational, educational and intellectual opportunities and in the absence of sensory or neurological disability. -
Sequence similarities
Contains 2 doublecortin domains. - Information by UniProt
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Database links
- Entrez Gene: 51473 Human
- Entrez Gene: 195208 Mouse
- Entrez Gene: 291130 Rat
- Omim: 605755 Human
- SwissProt: Q9UHG0 Human
- SwissProt: Q5DU00 Mouse
- SwissProt: D3ZR10 Rat
- Unigene: 61345 Human
see all -
Alternative names
- DCDC 2 antibody
- DCDC2 antibody
- DCDC2_HUMAN antibody
see all
Images
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All lanes : Anti-DCDC2/RU2 antibody (ab126539) at 1/100 dilution
Lane 1 : Mouse Brain (1 day old)
Lane 2 : Mouse Cortex (3 month old)
Lane 3 : Mouse Skeletal Muscle (Post natal, 0 day old)
Lane 4 : Mouse Skeletal Muscle (Embryonic, day 18)
Lane 5 : Mouse Placenta
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 52 kDa
Observed band size: 52 kDa
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab126539 has not yet been referenced specifically in any publications.