Product nameAnti-DCDC2/RU2 antibody
See all DCDC2/RU2 primary antibodies
DescriptionRabbit polyclonal to DCDC2/RU2
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse
Predicted to work with: Rat, Rabbit, Horse, Human, Pig, Chimpanzee, Macaque monkey, Gorilla, Orangutan
Synthetic peptide corresponding to Mouse DCDC2/RU2 aa 200-300 conjugated to keyhole limpet haemocyanin.
Database link: Q5DU00
- This antibody gave a positive signal in the following Mouse tissue lysates: Brain (1 day old); Cortex (3 month old); Skeletal Muscle (post natal, 0 day old); Skeletal Muscle (Embryonic, day 18); Placenta.
This product was previously labelled as DCDC2
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab126539 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Detects a band of approximately 52 kDa (predicted molecular weight: 52 kDa).|
FunctionMay be involved in neuronal migration during development of the cerebral neocortex.
Tissue specificityUbiquitously expressed. In brain, highly expressed in the entorhinal cortex, inferior temporal cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus.
Involvement in diseaseDefects in DCDC2 may be a cause of susceptibility to dyslexia type 2 (DYX2) [MIM:600202]; also known as specific reading disability type 2. Dyslexia is a relatively common, complex cognitive disorder that affects 5% to 10% of school-aged children. The disorder is characterized by an impairment of reading performance despite adequate motivational, educational and intellectual opportunities and in the absence of sensory or neurological disability.
Sequence similaritiesContains 2 doublecortin domains.
- Information by UniProt
- DCDC 2 antibody
- DCDC2 antibody
- DCDC2_HUMAN antibody
All lanes : Anti-DCDC2/RU2 antibody (ab126539) at 1/100 dilution
Lane 1 : Mouse Brain (1 day old)
Lane 2 : Mouse Cortex (3 month old)
Lane 3 : Mouse Skeletal Muscle (Post natal, 0 day old)
Lane 4 : Mouse Skeletal Muscle (Embryonic, day 18)
Lane 5 : Mouse Placenta
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 52 kDa
Observed band size: 52 kDa
ab126539 has not yet been referenced specifically in any publications.