Overview

  • Product name

  • Description

    Rabbit polyclonal to DCDC2/RU2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse
    Predicted to work with: Rat, Rabbit, Horse, Human, Pig, Chimpanzee, Macaque monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to Mouse DCDC2/RU2 aa 200-300 conjugated to keyhole limpet haemocyanin.
    Database link: Q5DU00

  • Positive control

    • This antibody gave a positive signal in the following Mouse tissue lysates: Brain (1 day old); Cortex (3 month old); Skeletal Muscle (post natal, 0 day old); Skeletal Muscle (Embryonic, day 18); Placenta.
  • General notes

     This product was previously labelled as DCDC2

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS

    Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab126539 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 52 kDa (predicted molecular weight: 52 kDa).

Target

  • Function

    May be involved in neuronal migration during development of the cerebral neocortex.
  • Tissue specificity

    Ubiquitously expressed. In brain, highly expressed in the entorhinal cortex, inferior temporal cortex, medial temporal cortex, hypothalamus, amygdala and hippocampus.
  • Involvement in disease

    Defects in DCDC2 may be a cause of susceptibility to dyslexia type 2 (DYX2) [MIM:600202]; also known as specific reading disability type 2. Dyslexia is a relatively common, complex cognitive disorder that affects 5% to 10% of school-aged children. The disorder is characterized by an impairment of reading performance despite adequate motivational, educational and intellectual opportunities and in the absence of sensory or neurological disability.
  • Sequence similarities

    Contains 2 doublecortin domains.
  • Information by UniProt
  • Database links

  • Alternative names

    • DCDC 2 antibody
    • DCDC2 antibody
    • DCDC2_HUMAN antibody
    • DCDC2A antibody
    • Doublecortin domain containing 2 antibody
    • doublecortin domain containing protein 2 antibody
    • Doublecortin domain-containing protein 2 antibody
    • HGNC:18141 antibody
    • KIAA1154 antibody
    • Protein RU2S antibody
    • RU 2 antibody
    • RU2 antibody
    • RU2S antibody
    • RU2S protein antibody
    see all

Images

  • All lanes : Anti-DCDC2/RU2 antibody (ab126539) at 1/100 dilution

    Lane 1 : Mouse Brain (1 day old)
    Lane 2 : Mouse Cortex (3 month old)
    Lane 3 : Mouse Skeletal Muscle (Post natal, 0 day old)
    Lane 4 : Mouse Skeletal Muscle (Embryonic, day 18)
    Lane 5 : Mouse Placenta

    Developed using the ECL technique.

    Performed under reducing conditions.

    Predicted band size: 52 kDa
    Observed band size: 52 kDa

References

ab126539 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab126539.
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