Key features and details
- Rabbit polyclonal to DCLK2
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-DCLK2 antibody
DescriptionRabbit polyclonal to DCLK2
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Human DCLK2 (C terminal).
Database link: NP_001035350
- Rat brain tissue and tissue lysate.
Previously labelled as DCAMKL2.
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Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months).
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityProtein A purified
Purification notesab106639 is purified by affinity chromatography via a peptide column.
Our Abpromise guarantee covers the use of ab106639 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 84 kDa.|
FunctionProtein kinase with a significantly reduced Ca2+/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm.
Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.
Contains 2 doublecortin domains.
Contains 1 protein kinase domain.
DomainThe doublecortin domains are involved in the colocalization with microtubules.
Cellular localizationCytoplasm > cytoskeleton. Colocalizes with microtubules.
- Information by UniProt
- CaMK-like CREB regulatory kinase 2 antibody
- CL2 antibody
- CLICK-II antibody
Western Blot of rat brain tissue lysate labeling DCLK2 with Anti-DCLK2 antibody (ab106639) at (1) 1 and (2) 2μg/ml.
Lane 1 : Anti-DCLK2 antibody (ab106639) at 1 µg/ml
Lane 2 : Anti-DCLK2 antibody (ab106639) at 2 µg/ml
All lanes : Rat brain tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 84 kDa
ab106639 at 5µg/ml, staining DCLK2 in Rat brain, using Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.
ab106639 has been referenced in 1 publication.
- Lipka J et al. Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites. EMBO J 35:302-18 (2016). PubMed: 26758546