Product nameAnti-DcR1 antibody
See all DcR1 primary antibodies
DescriptionRabbit polyclonal to DcR1
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
Recombinant fragment corresponding to Human DcR1 aa 30-230.
ARQEEVPQQTVAPQQQRHSFKGEECPAGSHRSEHTGACNPCTEGVDYTNA SNNEPSCFPCTVCKSDQKHKSSCTMTRDTVCQCKEGTFRNENSPEMCRKC SRCPSGEVQVSNCTSWDDIQCVEEFGANATVETPAAEETMNTSPGTPAPA AEETMNTSPGTPAPAAEETMTTSPGTPAPAAEETMTTSPGTPAPAAEETM IT
Database link: O14798
- Human spleen cell lysate.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab180777 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/2000. Predicted molecular weight: 27 kDa.|
|IHC-P||1/50 - 1/200.
ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
RelevanceDcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.
Cellular localizationCell Membrane and Cytoplasmic
- Antagonist decoy receptor for TRAIL/Apo 2L antibody
- CD263 antibody
- Cytotoxic TRAIL receptor 3 antibody
ab180777 has not yet been referenced specifically in any publications.